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Long Noncoding RNAs—Crucial Players Organizing the Landscape of the Neuronal Nucleus

Laboratory of Molecular Bases of Cell Motility, Nencki Institute of Experimental Biology, Polish Academy of Sciences, 02-093 Warsaw, Poland
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Academic Editor: Giuseppe Biamonti
Int. J. Mol. Sci. 2021, 22(7), 3478; https://doi.org/10.3390/ijms22073478
Received: 25 February 2021 / Revised: 22 March 2021 / Accepted: 24 March 2021 / Published: 27 March 2021
(This article belongs to the Special Issue Functions of Non-coding DNA Regions)
The ability to regulate chromatin organization is particularly important in neurons, which dynamically respond to external stimuli. Accumulating evidence shows that lncRNAs play important architectural roles in organizing different nuclear domains like inactive chromosome X, splicing speckles, paraspeckles, and Gomafu nuclear bodies. LncRNAs are abundantly expressed in the nervous system where they may play important roles in compartmentalization of the cell nucleus. In this review we will describe the architectural role of lncRNAs in the nuclei of neuronal cells. View Full-Text
Keywords: lncRNA; neuronal nucleus; nuclear architecture lncRNA; neuronal nucleus; nuclear architecture
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MDPI and ACS Style

Sas-Nowosielska, H.; Magalska, A. Long Noncoding RNAs—Crucial Players Organizing the Landscape of the Neuronal Nucleus. Int. J. Mol. Sci. 2021, 22, 3478. https://doi.org/10.3390/ijms22073478

AMA Style

Sas-Nowosielska H, Magalska A. Long Noncoding RNAs—Crucial Players Organizing the Landscape of the Neuronal Nucleus. International Journal of Molecular Sciences. 2021; 22(7):3478. https://doi.org/10.3390/ijms22073478

Chicago/Turabian Style

Sas-Nowosielska, Hanna, and Adriana Magalska. 2021. "Long Noncoding RNAs—Crucial Players Organizing the Landscape of the Neuronal Nucleus" International Journal of Molecular Sciences 22, no. 7: 3478. https://doi.org/10.3390/ijms22073478

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