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Volume 22
Issue 5
10.3390/ijms22052465
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Open AccessReview

Nutraceuticals in the Prevention of Viral Infections, including COVID-19, among the Pediatric Population: A Review of the Literature

by
Giuseppe Fabio Parisi
1,
Giuseppe Carota
2,
Carlo Castruccio Castracani
3,
Mariarita Spampinato
2,
Sara Manti
1,
Maria Papale
1,
Michelino Di Rosa
2,
Ignazio Barbagallo
4,* and
Salvatore Leonardi
1
1
Pediatric Pulmonology Unit, Department of Clinical and Experimental Medicine, University of Catania, Viale A. Doria 6, 95125 Catania, Italy
2
Department of Biomedical and Biotechnological Sciences, University of Catania, Via S. Sofia, 87 95125 Catania, Italy
3
The Children’s Hospital of Philadelphia (CHOP), Department of Pediatrics, Division of Hematology Leonard and Madlyn Abramson Pediatric Research Center, Philadelphia, PA 19104, USA
4
Department of Drug and Health Sciences, University of Catania, Viale A. Doria 6, 95125 Catania, Italy
*
Author to whom correspondence should be addressed.
Academic Editor: Claudiu T. Supuran
Int. J. Mol. Sci. 2021, 22(5), 2465; https://doi.org/10.3390/ijms22052465
Received: 27 January 2021 / Revised: 24 February 2021 / Accepted: 25 February 2021 / Published: 28 February 2021
(This article belongs to the Collection 21st Anniversary of IJMS: Advances in Biochemistry)
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Abstract

In recent years, there has been a growth in scientific interest in nutraceuticals, which are those nutrients in foods that have beneficial effects on health. Nutraceuticals can be extracted, used for food supplements, or added to foods. There has long been interest in the antiviral properties of nutraceuticals, which are especially topical in the context of the ongoing COVID-19 pandemic. Therefore, the purpose of this review is to evaluate the main nutraceuticals to which antiviral roles have been attributed (either by direct action on viruses or by modulating the immune system), with a focus on the pediatric population. Furthermore, the possible applications of these substances against SARS-CoV-2 will be considered. View Full-Text
Keywords: nutraceutical; children; viral infections; COVID-19; SARS-CoV2; probiotics; zinc; vitamin; resveratrol; quercetin; hesperidin; lactoferrin nutraceutical; children; viral infections; COVID-19; SARS-CoV2; probiotics; zinc; vitamin; resveratrol; quercetin; hesperidin; lactoferrin
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MDPI and ACS Style

Parisi, G.F.; Carota, G.; Castruccio Castracani, C.; Spampinato, M.; Manti, S.; Papale, M.; Di Rosa, M.; Barbagallo, I.; Leonardi, S. Nutraceuticals in the Prevention of Viral Infections, including COVID-19, among the Pediatric Population: A Review of the Literature. Int. J. Mol. Sci. 2021, 22, 2465. https://doi.org/10.3390/ijms22052465

AMA Style

Parisi GF, Carota G, Castruccio Castracani C, Spampinato M, Manti S, Papale M, Di Rosa M, Barbagallo I, Leonardi S. Nutraceuticals in the Prevention of Viral Infections, including COVID-19, among the Pediatric Population: A Review of the Literature. International Journal of Molecular Sciences. 2021; 22(5):2465. https://doi.org/10.3390/ijms22052465

Chicago/Turabian Style

Parisi, Giuseppe F.; Carota, Giuseppe; Castruccio Castracani, Carlo; Spampinato, Mariarita; Manti, Sara; Papale, Maria; Di Rosa, Michelino; Barbagallo, Ignazio; Leonardi, Salvatore. 2021. "Nutraceuticals in the Prevention of Viral Infections, including COVID-19, among the Pediatric Population: A Review of the Literature" Int. J. Mol. Sci. 22, no. 5: 2465. https://doi.org/10.3390/ijms22052465

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