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Review

Trajectory Shifts in Interdisciplinary Research of the Aryl Hydrocarbon Receptor—A Personal Perspective on Thymus and Skin

IUF-Leibniz Research Institute for Environmental Medicine, Auf’m Hennekamp 50, 40225 Düsseldorf, Germany
Academic Editor: Sang-Bae Han
Int. J. Mol. Sci. 2021, 22(4), 1844; https://doi.org/10.3390/ijms22041844
Received: 25 January 2021 / Revised: 8 February 2021 / Accepted: 10 February 2021 / Published: 12 February 2021
Identifying historical trajectories is a useful exercise in research, as it helps clarify important, perhaps even “paradigmatic”, shifts in thinking and moving forward in science. In this review, the development of research regarding the role of the transcription factor “aryl hydrocarbon receptor” (AHR) as a mediator of the toxicity of environmental pollution towards a link between the environment and a healthy adaptive response of the immune system and the skin is discussed. From this fascinating development, the opportunities for targeting the AHR in the therapy of many diseases become clear. View Full-Text
Keywords: thymus; immune system; skin; 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD); aryl hydrocarbon receptor (AHR); therapeutic target thymus; immune system; skin; 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD); aryl hydrocarbon receptor (AHR); therapeutic target
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MDPI and ACS Style

Esser, C. Trajectory Shifts in Interdisciplinary Research of the Aryl Hydrocarbon Receptor—A Personal Perspective on Thymus and Skin. Int. J. Mol. Sci. 2021, 22, 1844. https://doi.org/10.3390/ijms22041844

AMA Style

Esser C. Trajectory Shifts in Interdisciplinary Research of the Aryl Hydrocarbon Receptor—A Personal Perspective on Thymus and Skin. International Journal of Molecular Sciences. 2021; 22(4):1844. https://doi.org/10.3390/ijms22041844

Chicago/Turabian Style

Esser, Charlotte. 2021. "Trajectory Shifts in Interdisciplinary Research of the Aryl Hydrocarbon Receptor—A Personal Perspective on Thymus and Skin" International Journal of Molecular Sciences 22, no. 4: 1844. https://doi.org/10.3390/ijms22041844

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