Verteporfin-Loaded Mesoporous Silica Nanoparticles’ Topical Applications Inhibit Mouse Melanoma Lymphangiogenesis and Micrometastasis In Vivo
Abstract
:1. Introduction
2. Results
3. Discussion
4. Materials and Methods
4.1. Synthesis of Verteporfin-Loaded Mesoporous Silica Nanoparticles
4.2. In Vivo Melanoma Topical Treatment
4.3. Immunofluorescence and Immunohistochemistry of Tumors and Animal Specimens
4.4. Statistical Analysis
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Clemente, N.; Miletto, I.; Gianotti, E.; Sabbatini, M.; Invernizzi, M.; Marchese, L.; Dianzani, U.; Renò, F. Verteporfin-Loaded Mesoporous Silica Nanoparticles’ Topical Applications Inhibit Mouse Melanoma Lymphangiogenesis and Micrometastasis In Vivo. Int. J. Mol. Sci. 2021, 22, 13443. https://doi.org/10.3390/ijms222413443
Clemente N, Miletto I, Gianotti E, Sabbatini M, Invernizzi M, Marchese L, Dianzani U, Renò F. Verteporfin-Loaded Mesoporous Silica Nanoparticles’ Topical Applications Inhibit Mouse Melanoma Lymphangiogenesis and Micrometastasis In Vivo. International Journal of Molecular Sciences. 2021; 22(24):13443. https://doi.org/10.3390/ijms222413443
Chicago/Turabian StyleClemente, Nausicaa, Ivana Miletto, Enrica Gianotti, Maurizio Sabbatini, Marco Invernizzi, Leonardo Marchese, Umberto Dianzani, and Filippo Renò. 2021. "Verteporfin-Loaded Mesoporous Silica Nanoparticles’ Topical Applications Inhibit Mouse Melanoma Lymphangiogenesis and Micrometastasis In Vivo" International Journal of Molecular Sciences 22, no. 24: 13443. https://doi.org/10.3390/ijms222413443