The Importance of 6-Aminohexanoic Acid as a Hydrophobic, Flexible Structural Element
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Department of Analytical Chemistry, Medical University of Bialystok, 15-089 Bialystok, Poland
2
Department of Internal Medicine and Gastroenterology, Polish Red Cross Memorial Municipal Hospital, 79 Henryk Sienkiewicz Street, 15-003 Bialystok, Poland
*
Author to whom correspondence should be addressed.
Academic Editors: Ernest Giralt and Macarena Sánchez-Navarro
Int. J. Mol. Sci. 2021, 22(22), 12122; https://doi.org/10.3390/ijms222212122
Received: 5 October 2021
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Revised: 2 November 2021
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Accepted: 5 November 2021
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Published: 9 November 2021
(This article belongs to the Special Issue Design and Synthesis of Peptides: Impact on Current Biomedicine, Biotechnology, and Chemical Biology)
6-aminohexanoic acid is an ω-amino acid with a hydrophobic, flexible structure. Although the ω-amino acid in question is mainly used clinically as an antifibrinolytic drug, other applications are also interesting and important. This synthetic lysine derivative, without an α-amino group, plays a significant role in chemical synthesis of modified peptides and in the polyamide synthetic fibers (nylon) industry. It is also often used as a linker in various biologically active structures. This review concentrates on the role of 6-aminohexanoic acid in the structure of various molecules.
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Keywords:
6-aminohexanoic acid; antifibrynolytics; linker
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MDPI and ACS Style
Markowska, A.; Markowski, A.R.; Jarocka-Karpowicz, I. The Importance of 6-Aminohexanoic Acid as a Hydrophobic, Flexible Structural Element. Int. J. Mol. Sci. 2021, 22, 12122. https://doi.org/10.3390/ijms222212122
AMA Style
Markowska A, Markowski AR, Jarocka-Karpowicz I. The Importance of 6-Aminohexanoic Acid as a Hydrophobic, Flexible Structural Element. International Journal of Molecular Sciences. 2021; 22(22):12122. https://doi.org/10.3390/ijms222212122
Chicago/Turabian StyleMarkowska, Agnieszka, Adam R. Markowski, and Iwona Jarocka-Karpowicz. 2021. "The Importance of 6-Aminohexanoic Acid as a Hydrophobic, Flexible Structural Element" International Journal of Molecular Sciences 22, no. 22: 12122. https://doi.org/10.3390/ijms222212122
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