Endometriosis: Epidemiology, Classification, Pathogenesis, Treatment and Genetics (Review of Literature)
1
Laboratory of Cancer Genetics, Department of Pathology, Polish Mother’s Memorial Hospital Research Institute, Rzgowska 281/289, 93-338 Lodz, Poland
2
Department of Operative Gynaecology and Oncological Gynaecology, Polish Mother’s Memorial Hospital Research Institute, Rzgowska 281/289, 93-338 Lodz, Poland
*
Author to whom correspondence should be addressed.
Academic Editor: Kanako Hayashi
Int. J. Mol. Sci. 2021, 22(19), 10554; https://doi.org/10.3390/ijms221910554
Received: 26 August 2021
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Revised: 22 September 2021
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Accepted: 26 September 2021
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Published: 29 September 2021
(This article belongs to the Special Issue Protein and Nucleotide Engineering for Diagnoses and Biosensing)
Endometriosis is a “mysterious” disease and its exact cause has not yet been established. Among the etiological factors, congenital, environmental, epigenetic, autoimmune and allergic factors are listed. It is believed that the primary mechanism of the formation of endometriosis foci is retrograde menstruation, i.e., the passage of menstrual blood through the fallopian tubes into the peritoneal cavity and implantation of exfoliated endometrial cells. However, since this mechanism is also observed in healthy women, other factors must also be involved in the formation of endometriosis foci. Endometriosis is in many women the cause of infertility, chronic pain and the deterioration of the quality of life. It also represents a significant financial burden on health systems. The article presents a review of the literature on endometriosis—a disease affecting women throughout the world.
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Keywords:
endometriosis; diagnostic; treatment; biomarkers; genes
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MDPI and ACS Style
Smolarz, B.; Szyłło, K.; Romanowicz, H. Endometriosis: Epidemiology, Classification, Pathogenesis, Treatment and Genetics (Review of Literature). Int. J. Mol. Sci. 2021, 22, 10554. https://doi.org/10.3390/ijms221910554
AMA Style
Smolarz B, Szyłło K, Romanowicz H. Endometriosis: Epidemiology, Classification, Pathogenesis, Treatment and Genetics (Review of Literature). International Journal of Molecular Sciences. 2021; 22(19):10554. https://doi.org/10.3390/ijms221910554
Chicago/Turabian StyleSmolarz, Beata, Krzysztof Szyłło, and Hanna Romanowicz. 2021. "Endometriosis: Epidemiology, Classification, Pathogenesis, Treatment and Genetics (Review of Literature)" International Journal of Molecular Sciences 22, no. 19: 10554. https://doi.org/10.3390/ijms221910554
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