ERM Proteins at the Crossroad of Leukocyte Polarization, Migration and Intercellular Adhesion
Abstract
:1. Introduction
2. ERM Tools for Plasma Membrane-to-Cytoskeleton Bridging
3. ERMs in Leukocyte Polarization and Migration
3.1. Tethering and Rolling
3.2. Firm Adhesion
3.3. Transendothelial Migration
4. ERMs and Intercellular Adhesion: the Phagocytic Cup and the Immune Synapse as Paradigms of Ezrin- and Moesin-Mediated PM Organization in Leukocytes
4.1. The phagocytic Cup and the Phagosome
4.2. The Immune Synapse
5. ERMs and Immune Regulation
6. Conclusions and Future Perspectives
Author Contributions
Funding
Acknowledgments
Conflicts of Interest
References
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García-Ortiz, A.; Serrador, J.M. ERM Proteins at the Crossroad of Leukocyte Polarization, Migration and Intercellular Adhesion. Int. J. Mol. Sci. 2020, 21, 1502. https://doi.org/10.3390/ijms21041502
García-Ortiz A, Serrador JM. ERM Proteins at the Crossroad of Leukocyte Polarization, Migration and Intercellular Adhesion. International Journal of Molecular Sciences. 2020; 21(4):1502. https://doi.org/10.3390/ijms21041502
Chicago/Turabian StyleGarcía-Ortiz, Almudena, and Juan Manuel Serrador. 2020. "ERM Proteins at the Crossroad of Leukocyte Polarization, Migration and Intercellular Adhesion" International Journal of Molecular Sciences 21, no. 4: 1502. https://doi.org/10.3390/ijms21041502