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Long Non-Coding RNA Associated with Cholesterol Homeostasis and Its Involvement in Metabolic Diseases

Department of Biochemistry, BK21 Plus and Research Institute for Veterinary Science, School of Veterinary Medicine, Seoul National University, Seoul 08826, Korea
*
Author to whom correspondence should be addressed.
The authors contribute equally.
Int. J. Mol. Sci. 2020, 21(21), 8337; https://doi.org/10.3390/ijms21218337
Received: 20 October 2020 / Revised: 3 November 2020 / Accepted: 5 November 2020 / Published: 6 November 2020
(This article belongs to the Special Issue LncRNAs in Health and Disease)
Cholesterol is an essential cell component that functions to create and maintain all kinds of cell membranes and lipoprotein particles. It is crucial to maintain the proper amount of cholesterol at both the cellular and systemic level. Recently, the importance of cholesterol has been reported not only in various cell development processes but also in the development of diseases. Furthermore, the involvement of long non-coding RNAs (lncRNAs), which are regarded as important epigenetic regulators in gene expression, has also been reported in cholesterol homeostasis. It is thus necessary to summarize the research on lncRNAs related to cholesterol with increased interest. This review organized the role of lncRNAs according to the major issues in cholesterol homeostasis: efflux, metabolism and synthesis, and disease process. View Full-Text
Keywords: long non-coding RNA; lncRNA; cholesterol; disease long non-coding RNA; lncRNA; cholesterol; disease
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MDPI and ACS Style

Lee, K.-H.; Hwang, H.-J.; Cho, J.-Y. Long Non-Coding RNA Associated with Cholesterol Homeostasis and Its Involvement in Metabolic Diseases. Int. J. Mol. Sci. 2020, 21, 8337. https://doi.org/10.3390/ijms21218337

AMA Style

Lee K-H, Hwang H-J, Cho J-Y. Long Non-Coding RNA Associated with Cholesterol Homeostasis and Its Involvement in Metabolic Diseases. International Journal of Molecular Sciences. 2020; 21(21):8337. https://doi.org/10.3390/ijms21218337

Chicago/Turabian Style

Lee, Kang-Hoon; Hwang, Hyeon-Ji; Cho, Je-Yoel. 2020. "Long Non-Coding RNA Associated with Cholesterol Homeostasis and Its Involvement in Metabolic Diseases" Int. J. Mol. Sci. 21, no. 21: 8337. https://doi.org/10.3390/ijms21218337

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