Characterization of Rat Cardiovascular System by Anacrotic/Dicrotic Notches in the Condition of Increase/Decrease of NO Bioavailability
Abstract
:1. Introduction
2. Results
2.1. The Cross-Relationships of 34 HPs to the Difference between BP of Dicrotic and Anacrotic Notches
2.2. The Cross-Relationships of 34 HPs to the Time Interval between Dicrotic and Anacrotic Notches
2.3. Cross-Relathionships of DiN-AnN to 34 Rat HPs for Conditions of Increase/Decreased NO Bioavailability
3. Discussion
4. Materials and Methods
4.1. Ethical Approval
4.2. Animals, APW Measurement, and Data Evaluation
5. Conclusions
Supplementary Materials
Author Contributions
Funding
Conflicts of Interest
Abbreviations
AnN | Anacrotic notch |
APW | Arterial pulse waveform |
BP | Blood pressure |
DiN | Dicrotic notch |
GSNO | S-nitrosoglutathione |
HPs | Hemodynamic parameters |
l-NAME | N(ω)-nitro-l-arginine methyl ester |
NO | Nitric oxide |
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Tomasova, L.; Misak, A.; Kurakova, L.; Grman, M.; Ondrias, K. Characterization of Rat Cardiovascular System by Anacrotic/Dicrotic Notches in the Condition of Increase/Decrease of NO Bioavailability. Int. J. Mol. Sci. 2020, 21, 6685. https://doi.org/10.3390/ijms21186685
Tomasova L, Misak A, Kurakova L, Grman M, Ondrias K. Characterization of Rat Cardiovascular System by Anacrotic/Dicrotic Notches in the Condition of Increase/Decrease of NO Bioavailability. International Journal of Molecular Sciences. 2020; 21(18):6685. https://doi.org/10.3390/ijms21186685
Chicago/Turabian StyleTomasova, Lenka, Anton Misak, Lucia Kurakova, Marian Grman, and Karol Ondrias. 2020. "Characterization of Rat Cardiovascular System by Anacrotic/Dicrotic Notches in the Condition of Increase/Decrease of NO Bioavailability" International Journal of Molecular Sciences 21, no. 18: 6685. https://doi.org/10.3390/ijms21186685