Gut Microbiome Modulation for Preventing and Treating Pediatric Food Allergies
1
Department of Pediatrics and Neonatology, Guglielmo da Saliceto Hospital, 29121 Piacenza, Italy
2
Department of Translational Medical Science-Pediatric Section, University “Federico II”, 80131 Naples, Italy
3
ImmunoNutritionLab-CEINGE Advanced Biotechnologies, University “Federico II”, 80131 Naples, Italy
4
Task Force on Microbiome Studies, University of Naples “Federico II”, 80131 Naples, Italy
5
European Laboratory for the Investigation of Food-Induced Diseases, University of Naples “Federico II”, 80131 Naples, Italy
*
Author to whom correspondence should be addressed.
Int. J. Mol. Sci. 2020, 21(15), 5275; https://doi.org/10.3390/ijms21155275
Received: 22 June 2020
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Revised: 22 July 2020
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Accepted: 23 July 2020
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Published: 25 July 2020
(This article belongs to the Special Issue Gut Microbiota-Host Interactions: From Symbiosis to Dysbiosis)
The increasing prevalence and severity of pediatric food allergies (FA) demands innovative preventive and therapeutic strategies. Emerging evidence suggests a pivotal role for the gut microbiome in modulating susceptibility to FA. Studies have demonstrated that alteration of gut microbiome could precede FA, and that particular microbial community structures early in life could influence also the disease course. The identification of gut microbiome features in pediatric FA patients is driving new prevention and treatment approaches. This review is focused on the potential role of the gut microbiome as a target for FA prevention and treatment.
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Keywords:
gut microbiome; food allergy; dysbiosis
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MDPI and ACS Style
Di Costanzo, M.; Carucci, L.; Berni Canani, R.; Biasucci, G. Gut Microbiome Modulation for Preventing and Treating Pediatric Food Allergies. Int. J. Mol. Sci. 2020, 21, 5275. https://doi.org/10.3390/ijms21155275
AMA Style
Di Costanzo M, Carucci L, Berni Canani R, Biasucci G. Gut Microbiome Modulation for Preventing and Treating Pediatric Food Allergies. International Journal of Molecular Sciences. 2020; 21(15):5275. https://doi.org/10.3390/ijms21155275
Chicago/Turabian StyleDi Costanzo, Margherita, Laura Carucci, Roberto Berni Canani, and Giacomo Biasucci. 2020. "Gut Microbiome Modulation for Preventing and Treating Pediatric Food Allergies" International Journal of Molecular Sciences 21, no. 15: 5275. https://doi.org/10.3390/ijms21155275
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