Fighting AMR in the Healthcare Environment: Microbiome-Based Sanitation Approaches and Monitoring Tools

D’Accolti, Maria; Soffritti, Irene; Mazzacane, Sante; Caselli, Elisabetta

doi:10.3390/ijms20071535

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Fighting AMR in the Healthcare Environment: Microbiome-Based Sanitation Approaches and Monitoring Tools

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Section of Microbiology, Department of Medical Sciences, University of Ferrara, 44121 Ferrara, Italy

CIAS Research Centre, Department of Architecture and Medical Science, University of Ferrara, 44121 Ferrara, Italy

Author to whom correspondence should be addressed.

Int. J. Mol. Sci. 2019, 20(7), 1535; https://doi.org/10.3390/ijms20071535

Received: 27 February 2019 / Revised: 22 March 2019 / Accepted: 24 March 2019 / Published: 27 March 2019

(This article belongs to the Special Issue Drug Resistance: Mechanisms and New Strategies)

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Abstract

Healthcare-associated infections (HAIs) affect up to 15% of all hospitalized patients, representing a global concern. Major causes include the persistent microbial contamination of hospital environment, and the growing antimicrobial-resistance (AMR) of HAI-associated microbes. The hospital environment represents in fact a reservoir of potential pathogens, continuously spread by healthcare personnel, visiting persons and hospitalized patients. The control of contamination has been so far addressed by the use of chemical-based sanitation procedures, which however have limitations, as testified by the persistence of contamination itself and by the growing AMR of hospital microbes. Here we review the results collected by a microbial-based sanitation system, inspired by the microbiome balance principles, in obtaining more effective control of microbial contamination and AMR. Whatever the sanitation system used, an important aspect of controlling AMR and HAIs relates to the ability to check any variation of a microbial population rapidly and effectively, thus effective monitoring procedures are also described. View Full-Text

Keywords: healthcare-associated infections; antimicrobial resistance; sanitation; microbial technologies

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited

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MDPI and ACS Style

D’Accolti, M.; Soffritti, I.; Mazzacane, S.; Caselli, E. Fighting AMR in the Healthcare Environment: Microbiome-Based Sanitation Approaches and Monitoring Tools. Int. J. Mol. Sci. 2019, 20, 1535. https://doi.org/10.3390/ijms20071535

AMA Style

D’Accolti M, Soffritti I, Mazzacane S, Caselli E. Fighting AMR in the Healthcare Environment: Microbiome-Based Sanitation Approaches and Monitoring Tools. International Journal of Molecular Sciences. 2019; 20(7):1535. https://doi.org/10.3390/ijms20071535

Chicago/Turabian Style

D’Accolti, Maria, Irene Soffritti, Sante Mazzacane, and Elisabetta Caselli. 2019. "Fighting AMR in the Healthcare Environment: Microbiome-Based Sanitation Approaches and Monitoring Tools" International Journal of Molecular Sciences 20, no. 7: 1535. https://doi.org/10.3390/ijms20071535

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