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The Role of Exosomes in Pancreatic Cancer

Department of Surgery, Universitätsklinikum Erlangen, Krankenhausstraße 12, 91054 Erlangen, Germany
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Int. J. Mol. Sci. 2019, 20(18), 4332; https://doi.org/10.3390/ijms20184332
Received: 6 August 2019 / Revised: 20 August 2019 / Accepted: 29 August 2019 / Published: 4 September 2019
Pancreatic cancer remains one of the deadliest cancers in the world, as a consequence of late diagnosis, early metastasis and limited response to chemotherapy, under which conditions the potential mechanism of pancreatic cancer progression requires further study. Exosomes are membrane vesicles which are important in the progression, metastasis and chemoresistance in pancreatic cancer. Additionally, they have been verified to be potential as biomarkers, targets and drug carriers for pancreatic cancer treatment. Thus, studying the role of exosomes in pancreatic cancer is significant. This paper focuses on the role of exosomes in the proliferation, metastasis and chemoresistance, as well as their potential applications for pancreatic cancer. View Full-Text
Keywords: pancreatic cancer; exosomes; chemoresistance; biomarker pancreatic cancer; exosomes; chemoresistance; biomarker
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Lan, B.; Zeng, S.; Grützmann, R.; Pilarsky, C. The Role of Exosomes in Pancreatic Cancer. Int. J. Mol. Sci. 2019, 20, 4332.

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