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Is There a Role for the Non-Helicobacter pylori Bacteria in the Risk of Developing Gastric Cancer?

Department of Medicine, New York University School of Medicine, New York, NY 10016, USA
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Int. J. Mol. Sci. 2018, 19(5), 1353; https://doi.org/10.3390/ijms19051353
Received: 4 April 2018 / Revised: 26 April 2018 / Accepted: 27 April 2018 / Published: 3 May 2018
(This article belongs to the Special Issue Molecular Features Distinguishing Gastric Cancer Subtypes)
Helicobacter pylori is the most abundant bacterium in the gastric epithelium, and its presence has been associated with the risk of developing gastric cancer. As of 15 years ago, no other bacteria were associated with gastric epithelial colonization; but thanks to new methodologies, many other non-H. pylori bacteria have been identified. It is possible that non-H. pylori may have a significant role in the development of gastric cancer. Here, we discuss the specific role of H. pylori as a potential trigger for events that may be conducive to gastric cancer, and consider whether or not the rest of the gastric microbiota represent an additional risk in the development of this disease. View Full-Text
Keywords: H. pylori; gastric microbiota; gastric cancer; pro-inflammation H. pylori; gastric microbiota; gastric cancer; pro-inflammation
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MDPI and ACS Style

Li, J.; Perez Perez, G.I. Is There a Role for the Non-Helicobacter pylori Bacteria in the Risk of Developing Gastric Cancer? Int. J. Mol. Sci. 2018, 19, 1353. https://doi.org/10.3390/ijms19051353

AMA Style

Li J, Perez Perez GI. Is There a Role for the Non-Helicobacter pylori Bacteria in the Risk of Developing Gastric Cancer? International Journal of Molecular Sciences. 2018; 19(5):1353. https://doi.org/10.3390/ijms19051353

Chicago/Turabian Style

Li, Jackie, and Guillermo I. Perez Perez. 2018. "Is There a Role for the Non-Helicobacter pylori Bacteria in the Risk of Developing Gastric Cancer?" International Journal of Molecular Sciences 19, no. 5: 1353. https://doi.org/10.3390/ijms19051353

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