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Review

Platelets: Still a Therapeutical Target for Haemostatic Disorders

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Programa de Pós-graduação em Ciências e Biotecnologia, Instituto de Biologia, Universidade Federal Fluminense (UFF), Niterói CEP 24210-130, RJ, Brazil
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Programa de Pós-graduação em Patologia, Departamento de Patologia, Hospital Universitário Antônio Pedro (HUAP), Universidade Federal Fluminense (UFF), Niterói CEP 24030-215, RJ, Brazil
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LabTIF, Faculdade de Farmácia, Universidade Federal do Rio de Janeiro (UFRJ), Rio de Janeiro CEP 21941-590, RJ, Brazil
4
Interdisciplinary Center for Biotechnology Research, Federal University of Pampa, Antônio Trilha Avenue, P.O. Box 1847, São Gabriel/RS 97300-000, Brazil
*
Authors to whom correspondence should be addressed.
Int. J. Mol. Sci. 2014, 15(10), 17901-17919; https://doi.org/10.3390/ijms151017901
Received: 19 June 2014 / Revised: 26 August 2014 / Accepted: 23 September 2014 / Published: 7 October 2014
(This article belongs to the Section Biochemistry)
Platelets are cytoplasmatic fragments from bone marrow megakaryocytes present in blood. In this work, we review the basis of platelet mechanisms, their participation in syndromes and in arterial thrombosis, and their potential as a target for designing new antithrombotic agents. The option of new biotechnological sources is also explored. View Full-Text
Keywords: platelets; agonists; receptor; thrombosis; aspirin® platelets; agonists; receptor; thrombosis; aspirin®
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MDPI and ACS Style

Geraldo, R.B.; Sathler, P.C.; Lourenço, A.L.; Saito, M.S.; Cabral, L.M.; Rampelotto, P.H.; Castro, H.C. Platelets: Still a Therapeutical Target for Haemostatic Disorders. Int. J. Mol. Sci. 2014, 15, 17901-17919. https://doi.org/10.3390/ijms151017901

AMA Style

Geraldo RB, Sathler PC, Lourenço AL, Saito MS, Cabral LM, Rampelotto PH, Castro HC. Platelets: Still a Therapeutical Target for Haemostatic Disorders. International Journal of Molecular Sciences. 2014; 15(10):17901-17919. https://doi.org/10.3390/ijms151017901

Chicago/Turabian Style

Geraldo, Reinaldo B., Plínio C. Sathler, André L. Lourenço, Max S. Saito, Lucio M. Cabral, Pabulo H. Rampelotto, and Helena C. Castro 2014. "Platelets: Still a Therapeutical Target for Haemostatic Disorders" International Journal of Molecular Sciences 15, no. 10: 17901-17919. https://doi.org/10.3390/ijms151017901

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