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The Influence of Metal Stress on the Availability and Redox State of Ascorbate, and Possible Interference with Its Cellular Functions

Centre for Environmental Sciences, Hasselt University, Agoralaan Building D, Diepenbeek B-3590, Belgium
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Int. J. Mol. Sci. 2013, 14(3), 6382-6413; https://doi.org/10.3390/ijms14036382
Received: 1 February 2013 / Revised: 6 March 2013 / Accepted: 8 March 2013 / Published: 20 March 2013
(This article belongs to the Special Issue Abiotic and Biotic Stress Tolerance Mechanisms in Plants)
Worldwide, metals have been distributed to excessive levels in the environment due to industrial and agricultural activities. Plants growing on soils contaminated with excess levels of metals experience a disturbance of the cellular redox balance, which leads to an augmentation of reactive oxygen species (ROS). Even though the increased ROS levels can cause cellular damage, controlled levels play an important role in modulating signaling networks that control physiological processes and stress responses. Plants control ROS levels using their antioxidative defense system both under non-stress conditions, as well as under stress conditions such as exposure to excess metals. Ascorbate (AsA) is a well-known and important component of the plant’s antioxidative system. As primary antioxidant, it can reduce ROS directly and indirectly via ascorbate peroxidase in the ascorbate–glutathione cycle. Furthermore, AsA fulfills an essential role in physiological processes, some of which are disturbed by excess metals. In this review, known direct effects of excess metals on AsA biosynthesis and functioning will be discussed, as well as the possible interference of metals with the role of AsA in physiological and biochemical processes. View Full-Text
Keywords: metals; oxidative stress; reactive oxygen species (ROS); ascorbate; cellular redox signal metals; oxidative stress; reactive oxygen species (ROS); ascorbate; cellular redox signal
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MDPI and ACS Style

Bielen, A.; Remans, T.; Vangronsveld, J.; Cuypers, A. The Influence of Metal Stress on the Availability and Redox State of Ascorbate, and Possible Interference with Its Cellular Functions. Int. J. Mol. Sci. 2013, 14, 6382-6413. https://doi.org/10.3390/ijms14036382

AMA Style

Bielen A, Remans T, Vangronsveld J, Cuypers A. The Influence of Metal Stress on the Availability and Redox State of Ascorbate, and Possible Interference with Its Cellular Functions. International Journal of Molecular Sciences. 2013; 14(3):6382-6413. https://doi.org/10.3390/ijms14036382

Chicago/Turabian Style

Bielen, An, Tony Remans, Jaco Vangronsveld, and Ann Cuypers. 2013. "The Influence of Metal Stress on the Availability and Redox State of Ascorbate, and Possible Interference with Its Cellular Functions" International Journal of Molecular Sciences 14, no. 3: 6382-6413. https://doi.org/10.3390/ijms14036382

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