In the original publication [1], there were mistakes in the representative images for the PBS and FGF controls and FGF + Difluoroallicin (Figure 5). Specifically, in Figure 5, there were unintentional mistakes in incorporating representative CAM images from other archived files. Additionally, the error in the FGF + Difluoroallicin panel was due to inadvertent exchange with a panel from another contemporaneous study. The correct image for those three panels (PBS, FGF and FGF + Difluoroallicin) appears in the corrected figure. The authors apologize for these unintentional mistakes. However, the mean % inhibition of FGF-mediated angiogenesis by difluoroallicin (>60% inhibition) was unaffected, as shown in Figure 3. These changes in the representative images do not affect the conclusions regarding the biological activity of the compounds studied.
Figure 5 (Corrected):
Figure 5.
Representative images of CAM neovascularization induced by FGF (bFGF) and its inhibition by the various garlic-derived compounds, including ajoene (8), allicin (1) and difluoroallicin (12) each at 4 µg/20 µL/CAM. The images shown are representative single images selected for illustration of the general anti-angiogenesis efficacy of the organosulfur compounds and not for quantitative purposes.
This correction was approved by the Academic Editor. The original publication has also been updated.
Reference
- Block, E.; Bechand, B.; Gundala, S.; Vattekkatte, A.; Wang, K.; Mousa, S.S.; Godugu, K.; Yalcin, M.; Mousa, S.A. Fluorinated Analogs of Organosulfur Compounds from Garlic (Allium sativum): Synthesis, Chemistry and Anti-Angiogenesis and Antithrombotic Studies. Molecules 2017, 22, 2081. [Google Scholar] [CrossRef] [PubMed]
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