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Review

Petasis vs. Strecker Amino Acid Synthesis: Convergence, Divergence and Opportunities in Organic Synthesis

Department of Chemical and Physical Sciences, Faculty of Natural Sciences, Walter Sisulu University, Nelson Mandela Drive, Mthatha 5117, South Africa
Academic Editors: Ana Maria Gomez Neo and Carlos Fernández Marcos
Molecules 2021, 26(6), 1707; https://doi.org/10.3390/molecules26061707
Received: 20 February 2021 / Revised: 11 March 2021 / Accepted: 13 March 2021 / Published: 18 March 2021
(This article belongs to the Special Issue New Approach in Multicomponent Reactions)
α-Amino acids find widespread applications in various areas of life and physical sciences. Their syntheses are carried out by a multitude of protocols, of which Petasis and Strecker reactions have emerged as the most straightforward and most widely used. Both reactions are three-component reactions using the same starting materials, except the nucleophilic species. The differences and similarities between these two important reactions are highlighted in this review. View Full-Text
Keywords: amino acids; biomolecules; multicomponent reactions; peptides; Petasis; Strecker amino acids; biomolecules; multicomponent reactions; peptides; Petasis; Strecker
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MDPI and ACS Style

Masamba, W. Petasis vs. Strecker Amino Acid Synthesis: Convergence, Divergence and Opportunities in Organic Synthesis. Molecules 2021, 26, 1707. https://doi.org/10.3390/molecules26061707

AMA Style

Masamba W. Petasis vs. Strecker Amino Acid Synthesis: Convergence, Divergence and Opportunities in Organic Synthesis. Molecules. 2021; 26(6):1707. https://doi.org/10.3390/molecules26061707

Chicago/Turabian Style

Masamba, Wayiza. 2021. "Petasis vs. Strecker Amino Acid Synthesis: Convergence, Divergence and Opportunities in Organic Synthesis" Molecules 26, no. 6: 1707. https://doi.org/10.3390/molecules26061707

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