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Application of Conducting Polymer Nanostructures to Electrochemical Biosensors

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Department of Chemistry, Faculty of Science, Assiut University, Assiut 71516, Egypt
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Department of Chemical and Biomolecular Engineering, Sogang University, 35 Baekbeom-Ro, Mapo-Gu, Seoul 04107, Korea
*
Author to whom correspondence should be addressed.
Academic Editor: Carlos Alemán
Molecules 2020, 25(2), 307; https://doi.org/10.3390/molecules25020307
Received: 24 December 2019 / Revised: 10 January 2020 / Accepted: 10 January 2020 / Published: 12 January 2020
(This article belongs to the Special Issue Polymer Biosensor for Electrochemical Detection)
Over the past few decades, nanostructured conducting polymers have received great attention in several application fields, including biosensors, microelectronics, polymer batteries, actuators, energy conversion, and biological applications due to their excellent conductivity, stability, and ease of preparation. In the bioengineering application field, the conducting polymers were reported as excellent matrixes for the functionalization of various biological molecules and thus enhanced their performances as biosensors. In addition, combinations of metals or metal oxides nanostructures with conducting polymers result in enhancing the stability and sensitivity as the biosensing platform. Therefore, several methods have been reported for developing homogeneous metal/metal oxide nanostructures thin layer on the conducting polymer surfaces. This review will introduce the fabrications of different conducting polymers nanostructures and their composites with different shapes. We will exhibit the different techniques that can be used to develop conducting polymers nanostructures and to investigate their chemical, physical and topographical effects. Among the various biosensors, we will focus on conducting polymer-integrated electrochemical biosensors for monitoring important biological targets such as DNA, proteins, peptides, and other biological biomarkers, in addition to their applications as cell-based chips. Furthermore, the fabrication and applications of the molecularly imprinted polymer-based biosensors will be addressed in this review. View Full-Text
Keywords: conducting polymers; molecularly imprinted polymer; cell-based chip; nanotechnology; electrochemical sensor; biosensors conducting polymers; molecularly imprinted polymer; cell-based chip; nanotechnology; electrochemical sensor; biosensors
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MDPI and ACS Style

El-Said, W.A.; Abdelshakour, M.; Choi, J.-H.; Choi, J.-W. Application of Conducting Polymer Nanostructures to Electrochemical Biosensors. Molecules 2020, 25, 307.

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