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Article

Bioactive Compounds and Health-Promoting Properties of Pear (Pyrus communis L.) Fruits

1
Department of Fruit, Vegetable and Plant Nutraceutical Technology, Wroclaw University of Environmental and Life Sciences, Chelmonskiego 37 Street, 51-630 Wroclaw, Poland
2
Laboratory of Experimental Anticancer Therapy, Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Weigla 12 Street, 53-114 Wroclaw, Poland
3
Research Institute of Horticulture, Konstytucji 3 Maja 1/3 Street, 96-100 Skierniewice, Poland
*
Author to whom correspondence should be addressed.
Molecules 2020, 25(19), 4444; https://doi.org/10.3390/molecules25194444
Received: 21 August 2020 / Revised: 18 September 2020 / Accepted: 23 September 2020 / Published: 27 September 2020
Consuming food that is rich in antioxidants reduces the risk of developing chronic diseases and oxidative stress. Fruits and vegetables are an excellent source of substances with antioxidant and pro-health properties. Such raw materials, characterized by a high content of polyphenolic compounds and antioxidant capacity, include pear fruits. In this study, the concentrations of bioactive compounds, as well as the antioxidant, anti-inflammatory, and antiproliferative activity in fruits of five selected pear cultivars were determined and compared. LC–MS and UPLC–PDA methods were used to determine the polyphenolic, carotenoid, chlorophyll, and triterpenoid profiles and content, and the antioxidant activity was analyzed using DPPH and ferric-reducing ability of plasma (FRAP) tests. The anti-inflammatory activity was determined against COX-1 and COX-2 enzymes. The cytotoxic activity of the test compounds was assessed against six tumor cell lines. The results showed that the major group of phenolic compounds in all cultivars was phenolic acids. In the group of chromoplastic pigments, chlorophyllide a and 9-cis-β-carotene were the major compounds, while in the triterpene group, ursolic acid was dominant. The antioxidant potential correlated with the content of polyphenols and carotenoids, and was the strongest for the ‘Radana’ cultivar. The highest antiproliferative activity in all varieties was established for bladder cancer. View Full-Text
Keywords: UPLC-MS; pear; bioactive compounds; health-promoting properties; suitability for processing UPLC-MS; pear; bioactive compounds; health-promoting properties; suitability for processing
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MDPI and ACS Style

Kolniak-Ostek, J.; Kłopotowska, D.; Rutkowski, K.P.; Skorupińska, A.; Kruczyńska, D.E. Bioactive Compounds and Health-Promoting Properties of Pear (Pyrus communis L.) Fruits. Molecules 2020, 25, 4444. https://doi.org/10.3390/molecules25194444

AMA Style

Kolniak-Ostek J, Kłopotowska D, Rutkowski KP, Skorupińska A, Kruczyńska DE. Bioactive Compounds and Health-Promoting Properties of Pear (Pyrus communis L.) Fruits. Molecules. 2020; 25(19):4444. https://doi.org/10.3390/molecules25194444

Chicago/Turabian Style

Kolniak-Ostek, Joanna, Dagmara Kłopotowska, Krzysztof P. Rutkowski, Anna Skorupińska, and Dorota E. Kruczyńska. 2020. "Bioactive Compounds and Health-Promoting Properties of Pear (Pyrus communis L.) Fruits" Molecules 25, no. 19: 4444. https://doi.org/10.3390/molecules25194444

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