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Review

Brown Seaweeds for the Management of Metabolic Syndrome and Associated Diseases

Department of Pharmaceutical and Pharmacological Sciences, University of Padova, 35131 Padova, Italy
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Authors to whom correspondence should be addressed.
Academic Editor: Luigi Milella
Molecules 2020, 25(18), 4182; https://doi.org/10.3390/molecules25184182
Received: 9 July 2020 / Revised: 3 September 2020 / Accepted: 9 September 2020 / Published: 12 September 2020
Metabolic syndrome is characterized by the coexistence of different metabolic disorders which increase the risk of developing type 2 diabetes mellitus and cardiovascular diseases. Therefore, metabolic syndrome leads to a reduction in patients’ quality of life as well as to an increase in morbidity and mortality. In the last few decades, it has been demonstrated that seaweeds exert multiple beneficial effects by virtue of their micro- and macronutrient content, which could help in the management of cardiovascular and metabolic diseases. This review aims to provide an updated overview on the potential of brown seaweeds for the prevention and management of metabolic syndrome and its associated diseases, based on the most recent evidence obtained from in vitro and in vivo preclinical and clinical studies. Owing to their great potential for health benefits, brown seaweeds are successfully used in some nutraceuticals and functional foods for treating metabolic syndrome comorbidities. However, some issues still need to be tackled and deepened to improve the knowledge of their ADME/Tox profile in humans, in particular by finding validated indexes of their absorption and obtaining reliable information on their efficacy and long-term safety. View Full-Text
Keywords: seaweeds; Undaria pinnatifida; Ascophyllum nodosum; Laminaria japonica; Fucus vesiculosus; metabolic syndrome; cardiovascular diseases; hypertension; obesity; NAFLD; diabetes seaweeds; Undaria pinnatifida; Ascophyllum nodosum; Laminaria japonica; Fucus vesiculosus; metabolic syndrome; cardiovascular diseases; hypertension; obesity; NAFLD; diabetes
MDPI and ACS Style

Gabbia, D.; De Martin, S. Brown Seaweeds for the Management of Metabolic Syndrome and Associated Diseases. Molecules 2020, 25, 4182. https://doi.org/10.3390/molecules25184182

AMA Style

Gabbia D, De Martin S. Brown Seaweeds for the Management of Metabolic Syndrome and Associated Diseases. Molecules. 2020; 25(18):4182. https://doi.org/10.3390/molecules25184182

Chicago/Turabian Style

Gabbia, Daniela, and Sara De Martin. 2020. "Brown Seaweeds for the Management of Metabolic Syndrome and Associated Diseases" Molecules 25, no. 18: 4182. https://doi.org/10.3390/molecules25184182

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