Sangiangols A and B, Two New Dolabellanes from an Indonesian Marine Soft Coral, Anthelia sp.
Abstract
:1. Introduction
2. Results and Discussion
3. Materials and Methods
3.1. General Methods
3.2. Animal Material
3.3. Extraction and Isolation
3.3.1. Sangiangol A (1)
3.3.2. Sangiangol B (2)
3.4. Cytotoxicity Assay
Author Contributions
Funding
Acknowledgments
Conflicts of Interest
References
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Sample Availability: Not available. |
Position | Sangiangol A (1) | Sangiangol B (2) | ||||||
---|---|---|---|---|---|---|---|---|
δC * | mult. | δH ** | J in Hz | δC * | mult. | δH ** | J in Hz | |
1 | 50.2 | C | 44.7 | C | ||||
2a | 38.4 | CH2 | 1.63 | m *** | 42.8 | CH2 | 1.97 | m |
2b | 1.50 | ddd (14.4, 11.6, 7.2) | 1.25 | m *** | ||||
3a | 29.6 | CH2 | 2.10 | m *** | 25.0 | CH2 | 2.09 | dt (15.4, 10.0) |
3b | 1.73 | m *** | 1.64 | dd (13.3, 10.0) | ||||
4 | 150.1 | C | 149.3 | C | ||||
5a | 30.8 | CH2 | 2.42 | dt (14.6, 5.4) | 34.3 | CH2 | 2.45 | td (13.6, 4.6) |
5b | 2.22 | dd (14.6, 7.7) | 2.29 | brdd (13.6, 4.6) | ||||
6a | 24.4 | CH2 | 1.73 | m *** | 27.4 | CH2 | 1.79 | m |
6b | 1.73 | m *** | 1.50 | m | ||||
7 | 61.3 | CH | 3.06 | t (6.5) | 72.9 | CH | 3.56 | d (11.4) |
8 | 63.7 | C | 75.3 | C | ||||
9a | 36.0 | CH2 | 2.20 | dd (15.7, 3.0) | 33.6 | CH2 | 1.95 | dd (4.5, 2.7) |
9b | 2.00 | dd (15.7, 6.3) | 1.92 | dd (5.5, 1.6) | ||||
10 | 65.1 | CH | 4.40 | dd (6.3, 1.3) | 54.5 | CH | 3.02 | dd (5.4, 2.7) |
11 | 153.0 | C | 76.7 | C | ||||
12 | 127.0 | CH | 5.88 | brt (2.5) | 50.2 | CH | 2.18 | d (10.8, 2.0) |
13a | 29.7 | CH2 | 2.31 | m *** | 27.8 | CH2 | 1.89 | m |
13b | 2.10 | m *** | 1.60 | m | ||||
14a | 36.7 | CH2 | 1.84 | ddd (12.7, 9.0, 7.1) | 39.0 | CH2 | 1.79 | m |
14b | 1.63 | m *** | 1.74 | m | ||||
15 | 27.4 | CH3 | 1.09 | s | 24.0 | CH3 | 0.84 | s |
16a | 111.4 | CH2 | 4.76 | s | 112.7 | CH2 | 4.96 | s |
16b | 4.70 | s | 4.79 | s | ||||
17a | 67.2 | CH2 | 4.07 | d (12.2) | 67.2 | CH2 | 3.89 | d (11.4) |
17b | 3.38 | d (12.2) | 3.52 | d (11.4) | ||||
18 | 75.2 | C | ||||||
19 | 29.6 | CH3 | 1.21 | s | ||||
20 | 26.0 | CH3 | 1.26 | s |
Compound | Concentration (µg/mL) |
---|---|
1 | 5 |
2 | 10 |
3 | 10 |
4 | 1 |
5 | 0.5 |
6 | 10 |
7 | 1 |
8 | 10 |
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Hanif, N.; Murni, A.; Tanaka, J. Sangiangols A and B, Two New Dolabellanes from an Indonesian Marine Soft Coral, Anthelia sp. Molecules 2020, 25, 3803. https://doi.org/10.3390/molecules25173803
Hanif N, Murni A, Tanaka J. Sangiangols A and B, Two New Dolabellanes from an Indonesian Marine Soft Coral, Anthelia sp. Molecules. 2020; 25(17):3803. https://doi.org/10.3390/molecules25173803
Chicago/Turabian StyleHanif, Novriyandi, Anggia Murni, and Junichi Tanaka. 2020. "Sangiangols A and B, Two New Dolabellanes from an Indonesian Marine Soft Coral, Anthelia sp." Molecules 25, no. 17: 3803. https://doi.org/10.3390/molecules25173803