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Review

Quercetin, Epigallocatechin Gallate, Curcumin, and Resveratrol: From Dietary Sources to Human MicroRNA Modulation

1
Department of Pharmacy, Health and Nutritional Sciences, Department of Excellence 2018–2022, University of Calabria, Edificio Polifunzionale, 87036 Rende (CS), Italy
2
Department of Health Science, School of Medicine, University of Magna Graecia, Clinical Pharmacology Unit, Mater Domini Hospital, 88100 Catanzaro, Italy
*
Author to whom correspondence should be addressed.
Academic Editors: Susana M. Cardoso and Alessia Fazio
Molecules 2020, 25(1), 63; https://doi.org/10.3390/molecules25010063
Received: 30 November 2019 / Revised: 16 December 2019 / Accepted: 20 December 2019 / Published: 23 December 2019
(This article belongs to the Special Issue The Antioxidant Capacities of Natural Products 2019)
Epidemiologic studies suggest that dietary polyphenol intake is associated with a lower incidence of several non-communicable diseases. Although several foods contain complex mixtures of polyphenols, numerous factors can affect their content. Besides the well-known capability of these molecules to act as antioxidants, they are able to interact with cell-signaling pathways, modulating gene expression, influencing the activity of transcription factors, and modulating microRNAs. Here we deeply describe four polyphenols used as nutritional supplements: quercetin, resveratrol, epigallocatechin gallate (ECGC), and curcumin, summarizing the current knowledge about them, spanning from dietary sources to the epigenetic capabilities of these compounds on microRNA modulation. View Full-Text
Keywords: nutrients; antioxidants; common use; phenolic compounds nutrients; antioxidants; common use; phenolic compounds
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MDPI and ACS Style

Cione, E.; La Torre, C.; Cannataro, R.; Caroleo, M.C.; Plastina, P.; Gallelli, L. Quercetin, Epigallocatechin Gallate, Curcumin, and Resveratrol: From Dietary Sources to Human MicroRNA Modulation. Molecules 2020, 25, 63. https://doi.org/10.3390/molecules25010063

AMA Style

Cione E, La Torre C, Cannataro R, Caroleo MC, Plastina P, Gallelli L. Quercetin, Epigallocatechin Gallate, Curcumin, and Resveratrol: From Dietary Sources to Human MicroRNA Modulation. Molecules. 2020; 25(1):63. https://doi.org/10.3390/molecules25010063

Chicago/Turabian Style

Cione, Erika, Chiara La Torre, Roberto Cannataro, Maria C. Caroleo, Pierluigi Plastina, and Luca Gallelli. 2020. "Quercetin, Epigallocatechin Gallate, Curcumin, and Resveratrol: From Dietary Sources to Human MicroRNA Modulation" Molecules 25, no. 1: 63. https://doi.org/10.3390/molecules25010063

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