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Article

Electrochemical Preparation of Synergistic Nanoantimicrobials

by
Maria Chiara Sportelli
1,2,
Daniela Longano
1,
Elisabetta Bonerba
3,
Giuseppina Tantillo
3,
Luisa Torsi
1,
Luigia Sabbatini
1,
Nicola Cioffi
1,* and
Nicoletta Ditaranto
1,*
1
Dipartimento di Chimica, Università degli Studi di Bari Aldo Moro, via Orabona 4, I–70125 Bari, Italy
2
Dipartimento di Fisica, Istituto di Fotonica e Nanotecnologie UOS Bari, CNR, Via Amendola 173, I–70126 Bari, Italy
3
Dipartimento di Medicina Veterinaria, Università degli Studi di Bari Aldo Moro, Strada Prov. 62 per Casamassima, Km 3, I–70010 Valenzano (BA), Italy
*
Authors to whom correspondence should be addressed.
Molecules 2020, 25(1), 49; https://doi.org/10.3390/molecules25010049
Submission received: 15 November 2019 / Revised: 17 December 2019 / Accepted: 19 December 2019 / Published: 22 December 2019
(This article belongs to the Special Issue Frontiers of Antimicrobial Nanoparticles)
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Abstract

The rapid spreading of resistance among common bacterial pathogens towards the misused antibiotics/disinfectant agents has drawn much attention worldwide to bacterial infections. In light of this, the present work aimed at the realization of core–shell nanoparticles possessing remarkable antimicrobial properties thanks to the synergistic action of the metal core and the disinfectant shell. Copper nanoparticles stabilized by benzalkonium chloride were prepared, characterized, and implemented in poly-vinyl-methyl ketone to obtain nanoantimicrobial composite coatings. Bioactivity tests are reported, proving the excellent disinfectant properties of the proposed nanomaterials, as compared to one of the well-known and strongest silver-based nanoantimicrobials. Applications are also briefly described.
Keywords: copper nanoparticle; benzalkonium chloride; synergistic antimicrobial; nanomaterial; XPS; TEM; ETAAS copper nanoparticle; benzalkonium chloride; synergistic antimicrobial; nanomaterial; XPS; TEM; ETAAS

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MDPI and ACS Style

Sportelli, M.C.; Longano, D.; Bonerba, E.; Tantillo, G.; Torsi, L.; Sabbatini, L.; Cioffi, N.; Ditaranto, N. Electrochemical Preparation of Synergistic Nanoantimicrobials. Molecules 2020, 25, 49. https://doi.org/10.3390/molecules25010049

AMA Style

Sportelli MC, Longano D, Bonerba E, Tantillo G, Torsi L, Sabbatini L, Cioffi N, Ditaranto N. Electrochemical Preparation of Synergistic Nanoantimicrobials. Molecules. 2020; 25(1):49. https://doi.org/10.3390/molecules25010049

Chicago/Turabian Style

Sportelli, Maria Chiara, Daniela Longano, Elisabetta Bonerba, Giuseppina Tantillo, Luisa Torsi, Luigia Sabbatini, Nicola Cioffi, and Nicoletta Ditaranto. 2020. "Electrochemical Preparation of Synergistic Nanoantimicrobials" Molecules 25, no. 1: 49. https://doi.org/10.3390/molecules25010049

APA Style

Sportelli, M. C., Longano, D., Bonerba, E., Tantillo, G., Torsi, L., Sabbatini, L., Cioffi, N., & Ditaranto, N. (2020). Electrochemical Preparation of Synergistic Nanoantimicrobials. Molecules, 25(1), 49. https://doi.org/10.3390/molecules25010049

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