Next Article in Journal
Optimized Prediction of Reducing Sugars and Dry Matter of Potato Frying by FT-NIR Spectroscopy on Peeled Tubers
Previous Article in Journal
Practical Microwave Synthesis of Carbazole Aldehydes for the Development of DNA-Binding Ligands
Open AccessArticle

Enhancing the Yield of Bioactive Compounds from Sclerocarya birrea Bark by Green Extraction Approaches

Department of Analytical Chemistry, University of Granada, C/Fuentenueva s/n, 18071 Granada, Spain
Research and Development of Functional Food Centre (CIDAF), PTS Granada, Avda. Del Conocimiento s/n., Edificio BioRegion, 18016 Granada, Spain
Authors to whom correspondence should be addressed.
Molecules 2019, 24(5), 966;
Received: 12 February 2019 / Revised: 4 March 2019 / Accepted: 6 March 2019 / Published: 9 March 2019
(This article belongs to the Section Analytical Chemistry)
Sclerocarya birrea is a tree indigenous to Southern Africa with significant importance in rural livelihoods for food, medicine, and carving. The bark, which contains 10–20% tannin, provides several pharmacological benefits as an antidiabetic, anti-inflammatory, antimicrobial, anti-atherogenic, and antioxidant medication, among others. This study compared different extraction techniques used to recover bioactive compounds from marula bark. For this purpose, solid–liquid extraction, supercritical fluid extraction (SFE), and pressurized liquid extraction (PLE) were performed under selected conditions, using only “food-grade” solvents. The potential use of the proposed extraction methodologies was evaluated in term of yield, and the individual phenolic composition determined by HPLC–ESI–TOF–MS. PLE provided a high extraction yield in all experimental conditions. With regard to bioactive compounds composition, a total of 71 compounds, a significant percentage of which in a galloyl form, were distributed in five major categories. The largest number of compounds, mostly flavonoid aglycones, were extracted by PLE, generally when the extraction was developed at low temperatures. SFE did prove effective as a way of extracting antidiabetic proanthocyanidins. Advanced extraction techniques represent a powerful tool to obtain bioactive compounds from S. birrea bark, which can be used as supplements or food ingredients, promoting the valorization of this crop. View Full-Text
Keywords: Sclerocarya birrea; bark; green extraction; proanthocyanidins; PLE; SFE Sclerocarya birrea; bark; green extraction; proanthocyanidins; PLE; SFE
Show Figures

Graphical abstract

MDPI and ACS Style

Cádiz-Gurrea, M.L.; Lozano-Sánchez, J.; Fernández-Ochoa, Á.; Segura-Carretero, A. Enhancing the Yield of Bioactive Compounds from Sclerocarya birrea Bark by Green Extraction Approaches. Molecules 2019, 24, 966.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

Search more from Scilit
Back to TopTop