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An Economic, Modular, and Portable Skin Viscoelasticity Measurement Device for In Situ Longitudinal Studies

1
Department of Mechanical Engineering, Johns Hopkins University, Baltimore, MD 21218, USA
2
Department of Embryology, Carnegie Institution for Science, Baltimore, MD 21218, USA
3
Department of Bioinformatics, Southern University of Science and Technology, Shenzhen 518055, China
*
Author to whom correspondence should be addressed.
Academic Editor: Yi Zhang
Molecules 2019, 24(5), 907; https://doi.org/10.3390/molecules24050907
Received: 14 January 2019 / Revised: 23 February 2019 / Accepted: 1 March 2019 / Published: 5 March 2019
(This article belongs to the Special Issue Selected Papers on IEEE NANOMED 2018)
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Abstract

A indentation-based device to measure tissue mechanical property was designed and built using over-the-counter and 3D-printed parts. The device costs less than 100 USD and is capable of measuring samples of various geometry because of its modular design. The device is light-weight, thus portable, for measurements that can be performed at different sites. It was demonstrated that the measurement results obtained using our device are comparable to previous observations. The elastic shear modulus of the human skin was in the range of 2 kPa to 8 kPa, and skin tissues in old mice were stiffer than young mice. Mechanical properties of the skin tissues belonging to the same test subject varied depending on the location of the measurement. In conclusion, because our device is economic, modular, portable, and robust, it is suitable to serve as a standard measurement platform for studying tissue mechanics. View Full-Text
Keywords: viscoelastic property; skin tissue; age; indentation-based mechanical analyzer; Prony model viscoelastic property; skin tissue; age; indentation-based mechanical analyzer; Prony model
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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Park, S.; Tao, J.; Sun, L.; Fan, C.-M.; Chen, Y. An Economic, Modular, and Portable Skin Viscoelasticity Measurement Device for In Situ Longitudinal Studies. Molecules 2019, 24, 907.

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