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Open AccessReview

Anti-Inflammatory and Anticancer Properties of Bioactive Compounds from Sesamum indicum L.—A Review

1
Division of Gastroenterology, Department of Internal Medicine, Wan Fang Hospital, Taipei Medical University, Taipei 116, Taiwan
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School of Medicine, College of Medicine, Taipei Medical University, Taipei 110, Taiwan
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Integrative Therapy Center for Gastroenterologic Cancers, Wan Fang Hospital, Taipei Medical University, Taipei 116, Taiwan
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School of Chemical, Biological, Materials Engineering and Sciences, Mapúa University, 1002 Metro Manila, Philippines
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Department of Athletics Sports, College of Humanities and Social Sciences, Chang Jung Christian University, Tainan 711, Taiwan
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School of Pharmacy, College of Pharmacy, Taipei Medical University, Taipei 110, Taiwan
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College of Acupuncture and Oriental Medicine, Houston, TX 77063, USA
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Department of Medical Sciences Industry, College of Health Sciences, Chang Jung Christian University, Tainan 711, Taiwan
*
Author to whom correspondence should be addressed.
Molecules 2019, 24(24), 4426; https://doi.org/10.3390/molecules24244426
Received: 9 November 2019 / Revised: 28 November 2019 / Accepted: 3 December 2019 / Published: 4 December 2019
(This article belongs to the Special Issue Food and Drug Analysis)
The use of foodstuff as natural medicines has already been established through studies demonstrating the pharmacological activities that they exhibit. Knowing the nutritional and pharmacological significance of foods enables the understanding of their role against several diseases. Among the foods that can potentially be considered as medicine, is sesame or Sesamum indicum L., which is part of the Pedaliaceae family and is composed of its lignans such as sesamin, sesamol, sesaminol and sesamolin. Its lignans have been widely studied and are known to possess antiaging, anticancer, antidiabetes, anti-inflammatory and antioxidant properties. Modern chronic diseases, which can transform into clinical diseases, are potential targets of these lignans. The prime example of chronic diseases is rheumatic inflammatory diseases, which affect the support structures and the organs of the body and can also develop into malignancies. In line with this, studies emphasizing the anti-inflammatory and anticancer activities of sesame have been discussed in this review.
Keywords: anti-inflammatory; anti-cancer; sesame extracts; sesame oil; Sesamum indicum L. anti-inflammatory; anti-cancer; sesame extracts; sesame oil; Sesamum indicum L.
MDPI and ACS Style

Wu, M.-S.; Aquino, L.B.B.; Barbaza, M.Y.U.; Hsieh, C.-L.; Castro-Cruz, K.A.D.; Yang, L.-L.; Tsai, P.-W. Anti-Inflammatory and Anticancer Properties of Bioactive Compounds from Sesamum indicum L.—A Review. Molecules 2019, 24, 4426.

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