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Levels of Trace Elements in the Aqueous Humor of Cataract Patients Measured by the Inductively Coupled Plasma Optical Emission Spectrometry

1
Department of Retina and Vitreo and nd Surgery, Medical University of Lublin, Chmielna 1, 20-079 Lublin, Poland
2
Department of Analytical Chemistry, Medical University of Lublin, Chodźki 4A, 20-093 Lublin, Poland
3
Faculty of Chemistry, Department of Analytical Chemistry, Adam Mickiewicz University in Poznań, 89B Umultowska Street, 61-614 Poznan, Poland
4
Department of Applied Mathematics, University of Technology, Nadbystrzycka 38D, 20-618 Lublin, Poland
*
Author to whom correspondence should be addressed.
Molecules 2019, 24(22), 4127; https://doi.org/10.3390/molecules24224127
Received: 2 October 2019 / Revised: 12 November 2019 / Accepted: 13 November 2019 / Published: 14 November 2019
(This article belongs to the Section Analytical Chemistry)
Trace elements play an important role in the pathogenesis of several serious ophthalmological disorders, such as glaucoma, age-related macular degeneration (AMD), diabetic retinopathy, cataract, etc. This study aimed to measure alterations of chemical elements’ (67) levels in the aqueous humor of patients undergoing cataract surgery. The pilot study included 115 patients, (age 74 ± 7.27, female 64.35%, male 35.65%). The aqueous levels of elements were measured by the use of the inductively coupled plasma optical emission spectrometry (ICP-OES), quality controlled with certified standards. The classification of elements based on their concentration was achieved by hierarchical cluster analysis. This is the first screening study that quantifies over 60 elements which are present in the fluid from the anterior chamber of the eye of cataract patients. The obtained results can be suitable for understanding and identifying the causes that may play a role in the initiation and progression of lens opacity. View Full-Text
Keywords: trace elements; ICP-OES; cataract; the aqueous humor trace elements; ICP-OES; cataract; the aqueous humor
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MDPI and ACS Style

Dolar-Szczasny, J.; Święch, A.; Flieger, J.; Tatarczak-Michalewska, M.; Niedzielski, P.; Proch, J.; Majerek, D.; Kawka, J.; Mackiewicz, J. Levels of Trace Elements in the Aqueous Humor of Cataract Patients Measured by the Inductively Coupled Plasma Optical Emission Spectrometry. Molecules 2019, 24, 4127.

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