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Molecules 2018, 23(8), 1962;

Atriplex mollis Desf. Aerial Parts: Extraction Procedures, Secondary Metabolites and Color Analysis

Unité de Recherche Valorisation des Ressources Naturelles, Molécules Bioactives et Analyses Physicochimiques et Biologiques, Université Frères Mentouri, Constantine 1, Route d’Aïn El Bey, 25000 Constantine, Algeria
Department of Pharmacy, University “G. d’Annunzio” of Chieti-Pescara, Via dei Vestini 31, 66100 Chieti, Italy
Department of Drug Chemistry and Technologies, Sapienza University of Rome, P.le Aldo Moro 5, 00185 Rome, Italy
Department of Experimental Medicine, Sapienza University of Rome, P.le Aldo Moro 5, 00185 Rome, Italy
Author to whom correspondence should be addressed.
Received: 26 July 2018 / Revised: 2 August 2018 / Accepted: 5 August 2018 / Published: 6 August 2018
(This article belongs to the Special Issue Natural Product Pharmacology and Medicinal Chemistry)
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A method using high-performance liquid chromatography coupled with a photodiode array detector was proposed for the rapid characterization of different phenolic constituents from the extracts of Atriplex mollis aerial parts. Atriplex species are known for their multiple biological activities, but no information is available in the literature about A. mollis. With the aim to firstly characterize the main secondary metabolites of this plant, so as to orient better the biological evaluation, we applied three different extraction procedures and compared the chromatographic results. Microwave-assisted extraction gave the best yield and recovery of important compounds such as gallic acid, catechin, chlorogenic acid, p-OH benzoic acid, rutin, sinapinic acid, t-ferulic acid, naringenin and benzoic acid. These constituents belong to three important chemical classes: phenolic acids, flavonoids and monoterpenes. Color evaluation and analysis of chlorophylls (a and b) and carotenoids complete the preliminary profile of this plant. From these analyses, Atriplex mollis is a source of bioactive compounds (especially rutin, t-ferulic acid and gallic acid) and could be recommended as a plant of phyto-pharmaceutical relevance, opening new perspectives on this salt-tolerant plant. View Full-Text
Keywords: Atriplex mollis; SFE; MAE; HPLC-PDA; color analysis; pigments Atriplex mollis; SFE; MAE; HPLC-PDA; color analysis; pigments

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Boutaoui, N.; Zaiter, L.; Benayache, F.; Benayache, S.; Cacciagrano, F.; Cesa, S.; Secci, D.; Carradori, S.; Giusti, A.M.; Campestre, C.; Menghini, L.; Locatelli, M. Atriplex mollis Desf. Aerial Parts: Extraction Procedures, Secondary Metabolites and Color Analysis. Molecules 2018, 23, 1962.

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