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Molecules 2018, 23(7), 1765; https://doi.org/10.3390/molecules23071765

Ionic Liquid Solutions as a Green Tool for the Extraction and Isolation of Natural Products

School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Wenhua Road 103, Shenyang 110016, China
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Received: 11 June 2018 / Revised: 13 July 2018 / Accepted: 14 July 2018 / Published: 18 July 2018
(This article belongs to the Special Issue Ionic Liquids for Chemical and Biochemical Applications)
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Abstract

In the past few years, the application of ionic liquids (ILs) had attracted more attention of the researchers. Many studies focused on extracting active components from traditional herbals using ILs as alternative solvents so as to address the issue caused by the traditional methods for extraction of natural products (NPs) with organic chemical reagents. Through the summary of reported research work, an overview was presented for the application of ILs or IL-based materials in the extraction of NPs, including flavonoids, alkaloids, terpenoids, phenylpropanoids and so on. Here, we mainly describe the application of ILs to rich the extraction of critical bioactive constituents that were reported possessing multiple therapeutic effects or pharmacological activities, from medicinal plants. This review could shed some light on the wide use of ILs in the field of natural products chemistry to further reduce the environmental damage caused by large quantity of organic chemical reagents. View Full-Text
Keywords: ionic liquids; bioactive natural products; herbals; extraction and isolation; flavonoids; alkaloids; terpenoids; phenylpropanoids ionic liquids; bioactive natural products; herbals; extraction and isolation; flavonoids; alkaloids; terpenoids; phenylpropanoids
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Xiao, J.; Chen, G.; Li, N. Ionic Liquid Solutions as a Green Tool for the Extraction and Isolation of Natural Products. Molecules 2018, 23, 1765.

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