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Molecules 2018, 23(7), 1588;

Chemical Structures and Biological Activities of Limonoids from the Genus Swietenia (Meliaceae)

School of Pharmacy, Anhui University of Chinese Medicine, Hefei 230012, China
Synergetic Innovation Center of Anhui Authentic Chinese Medicine Quality Improvement, Hefei 230012, China
Natural Products Research Laboratories, Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC 27599-7568, USA
Chinese Medicine Research and Development Center, China Medical University and Hospital, Taichung 40402, Taiwan
Authors to whom correspondence should be addressed.
Received: 29 May 2018 / Revised: 20 June 2018 / Accepted: 26 June 2018 / Published: 29 June 2018
PDF [1427 KB, uploaded 29 June 2018]


Swietenia is a genus in the plant family Meliaceae. This genus contains seven to eight known species, found in the tropical and subtropical regions of the Americas and West Africa. Thus far, more than 160 limonoids have been isolated from four species of the genus Swietenia. Limonoids are rich in structure type and biological activity, and these compounds are the main active components in the Swietenia species. This paper will give a comprehensive overview of the recent phytochemical and pharmacological research on the terpenes from Swietenia plants and encourage further drug discovery research. View Full-Text
Keywords: genus Swietenia; limonoids; chemical components; biological activities genus Swietenia; limonoids; chemical components; biological activities

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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Sun, Y.-P.; Jin, W.-F.; Wang, Y.-Y.; Wang, G.; Morris-Natschke, S.L.; Liu, J.-S.; Wang, G.-K.; Lee, K.-H. Chemical Structures and Biological Activities of Limonoids from the Genus Swietenia (Meliaceae). Molecules 2018, 23, 1588.

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