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Molecules 2018, 23(5), 1089;

Nutraceutical and Ethnopharmacological Properties of Vangueria infausta subsp. infausta

Medicinal Plants and Economic Development (MPED) Research Centre, Department of Botany, University of Fort Hare, Private Bag X1314, Alice 5700, South Africa
Academic Editor: Francesca Giampieri
Received: 17 April 2018 / Revised: 2 May 2018 / Accepted: 3 May 2018 / Published: 4 May 2018
(This article belongs to the Special Issue Nutraceuticals and Their Medicinal Importance)
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Vangueria infausta subsp. infausta (VI) is a nutraceutical with plant parts valued in several cultures for its medicinal properties. Traditionally, VI is used against gastro-intestinal disorders, malaria, pneumonia, cough, menstrual problems, parasitic worms, chest complaints, snake bites, infertility, fever, candidiasis and abdominal pains. This study aims to critically summarize the nutraceutical properties, phytochemistry and pharmacology of VI with a view to provide baseline data required for further investigations on this plant. Relevant information on the nutraceutical and ethnopharmacological properties of VI was collected from established scientific databases such as ScienceDirect, SciFinder, PubMed, Google Scholar, Medline, and SCOPUS. Additionally, books, book chapters and conference papers were also consulted to access other important information. Comparative analysis of the literature revealed that VI is an important neutraceutical plant in east and southern Africa, used as herbal medicine in 69% of the countries where the species is native. Phytochemical studies revealed the presence in VI of fatty acids, flavonoids, iridoid lactones and triterpenoids. Based on in vitro and animal studies, the species exhibited antibacterial, antimycobacterial, antifungal, anti-inflammatory, antileishmanial, antioxidant, antiplasmodial, antifeedant and prostaglandin synthesis inhibitory activities. Pharmacological studies have provided supporting evidence for the therapeutic value of VI, however, detailed toxicological and clinical trials are required to assess efficacy of the species. View Full-Text
Keywords: ethnopharmacological; nutraceutical; rubiaceae; tropical Africa; Vangueria infausta subsp. infausta ethnopharmacological; nutraceutical; rubiaceae; tropical Africa; Vangueria infausta subsp. infausta

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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Maroyi, A. Nutraceutical and Ethnopharmacological Properties of Vangueria infausta subsp. infausta. Molecules 2018, 23, 1089.

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