8-Bit Adder and Subtractor with Domain Label Based on DNA Strand Displacement
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College of Mathematics and Computer Science, Zhejiang Normal University, Jinhua 321004, China
2
College of Nuclear Science and Engineering, Sanmen Institute of technicians, Sanmen 317100, China
3
Key Laboratory of Advanced Design and Intelligent Computing (Dalian University) Ministry of Education, Dalian 116622, China
*
Author to whom correspondence should be addressed.
Academic Editor: Xiangxiang Zeng
Molecules 2018, 23(11), 2989; https://doi.org/10.3390/molecules23112989
Received: 16 October 2018
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Revised: 10 November 2018
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Accepted: 13 November 2018
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Published: 15 November 2018
(This article belongs to the Special Issue Molecular Computing and Bioinformatics)
DNA strand displacement, which plays a fundamental role in DNA computing, has been widely applied to many biological computing problems, including biological logic circuits. However, there are many biological cascade logic circuits with domain labels based on DNA strand displacement that have not yet been designed. Thus, in this paper, cascade 8-bit adder/subtractor with a domain label is designed based on DNA strand displacement; domain t and domain f represent signal 1 and signal 0, respectively, instead of domain t and domain f are applied to representing signal 1 and signal 0 respectively instead of high concentration and low concentration high concentration and low concentration. Basic logic gates, an amplification gate, a fan-out gate and a reporter gate are correspondingly reconstructed as domain label gates. The simulation results of Visual DSD show the feasibility and accuracy of the logic calculation model of the adder/subtractor designed in this paper. It is a useful exploration that may expand the application of the molecular logic circuit.
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Keywords:
DNA strand displacement; cascade; 8-bit adder/subtractor; domain label
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MDPI and ACS Style
Han, W.; Zhou, C. 8-Bit Adder and Subtractor with Domain Label Based on DNA Strand Displacement. Molecules 2018, 23, 2989. https://doi.org/10.3390/molecules23112989
AMA Style
Han W, Zhou C. 8-Bit Adder and Subtractor with Domain Label Based on DNA Strand Displacement. Molecules. 2018; 23(11):2989. https://doi.org/10.3390/molecules23112989
Chicago/Turabian StyleHan, Weixuan, and Changjun Zhou. 2018. "8-Bit Adder and Subtractor with Domain Label Based on DNA Strand Displacement" Molecules 23, no. 11: 2989. https://doi.org/10.3390/molecules23112989
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