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Molecules 2018, 23(11), 2985;

Multidisciplinary Investigations on Galphimia glauca: A Mexican Medicinal Plant with Pharmacological Potential

Tecnologico de Monterrey, School of Engineering and Sciences, Campus Queretaro, Av. Epigmenio González No. 500, Fracc. San Pablo, Queretaro CP 76130, Mexico
Área Académica de Ciencias Agrícolas y Forestales, Instituto de Ciencias Agropecuarias, Universidad Autónoma del Estado de Hidalgo, Tulancingo CP 42000, Mexico
Centro de Investigación y Desarrollo Tecnológico en Electroquímica (CIDETEQ), Parque Tecnológico, Querétaro S/N, Sanfandila. Pedro Escobedo, Querétaro CP 76703, Mexico
Tecnologico de Monterrey, School of Engineering and Sciences, Campus Monterrey, Ave. Eugenio Garza Sada 2501, Monterrey CP 64849, Mexico
Centro de Investigación en Biotecnología (CEIB), Universidad Autónoma del Estado de Morelos (UAEM), Cuernavaca CP 62209, Mexico
Author to whom correspondence should be addressed.
Received: 19 October 2018 / Revised: 9 November 2018 / Accepted: 14 November 2018 / Published: 15 November 2018
(This article belongs to the Section Natural Products Chemistry)
Full-Text   |   PDF [1725 KB, uploaded 15 November 2018]   |  


Galphimia glauca (Cav.) Kuntze is an important endemic plant species, which possesses many medicinal properties and has been used in the Mexican traditional medicine for its sedative, anxiolytic, anticonvulsant, antiasthmatic and antiallergic properties. The therapeutic properties of this plant are mainly due to the presence of diverse bioactive compounds such as flavonoids, triterpenoids, and phenolics. Several triterpenoids and flavonoids compounds have been isolated and identified. Modern studies have demonstrated many biological activities such as anti-inflammatory, antidiarrheal, gastroenteritis, antimalarial and cytotoxic activities. Nevertheless, many studies are restricted to the crude extract, and many bioactive compounds are yet to be identified and validated according to its traditional use. However, its commercial exploitation and use are highly limited due to the non-availability of enough plant material and lack of knowledge about its agronomical practices. Moreover, the misinterpretation and mislabeling of closely related species of the genus Galphimia Cav. as G. glauca or G. gracilis is a common problem for its rigorous scientific study and commercial exploitation. The present review provides comprehensive knowledge based on the available scientific literature. To the best of our knowledge, this is the first review on G. glauca. This comprehensive information will certainly provide a guide for the better understanding and utilization of G. glauca for its scientific and industrial exploitation. View Full-Text
Keywords: Galphimia glauca; phytochemicals; anxiety; biotechnology Galphimia glauca; phytochemicals; anxiety; biotechnology

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Sharma, A.; Angulo-Bejarano, P.I.; Madariaga-Navarrete, A.; Oza, G.; Iqbal, H.M.N.; Cardoso-Taketa, A.; Luisa Villarreal, M. Multidisciplinary Investigations on Galphimia glauca: A Mexican Medicinal Plant with Pharmacological Potential. Molecules 2018, 23, 2985.

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