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Molecules 2017, 22(8), 1283;

Three New Sesquiterpene Glycosides from the Rhizomes of Trillium tschonoskii

School of Traditional Chinese Medicine, Guangdong Pharmaceutical University, Guangzhou 510006, China
Beijing Institute of Radiation Medicine, No. 27, Taiping Road, Beijing 100850, China
Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences, Beijing 100193, China
Author to whom correspondence should be addressed.
Received: 24 June 2017 / Revised: 1 August 2017 / Accepted: 1 August 2017 / Published: 2 August 2017
(This article belongs to the Special Issue Diversity of Terpenoids)
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Three new sesquiterpene glycosides, possessing a rare aglycone with a sulfonyl between C-1 and C-15 positions, named 3-(3′E-7′R,8′-dihydroxy-4′,8′-dimethyl-3′-nonenyl)-2,5-dihydro-1,1-dioxo-thiophen 7′-O-β-d-glucopyranosyl-(1→4)-O-β-d-glucopyranosyl-(1→4)-O-β-d-glucopyranoside (1), 3-(3′E-7′R,8′-dihydroxy-4′,8′-dimethyl-3′-nonenyl)-2,5-dihydro-1,1-dioxo-thiophen 7′-O-β-d-glucopyranosyl-(1→4)-O-β-d-glucopyranoside (2), and 3-(3′E-7′R,8′-dihydroxy-4′,8′-dimethyl-3′-nonenyl)-2,5-dihydro-1,1-dioxo-thiophen 7′-O-β-d-glucopyranosyl-6′-O-acetyl-(1→4)-O-β-d-glucopyranosyl-(1→4)-O-β-d-glucopyranoside (3), respectively, were isolated from the rhizomes of Trillium tschonoskii. Their structures were established on the basis of spectroscopic data, including HR-ESI-MS, IR, 1D and 2D NMR. The cytotoxic properties of the three compounds were investigated using human hepatic L02 cells. View Full-Text
Keywords: Trillium tschonoskii; sesquiterpene glycosides; separation Trillium tschonoskii; sesquiterpene glycosides; separation

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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Yang, J.; Yang, Y.-J.; Sun, X.-G.; Zhang, J.; Zhao, Y.; Wang, B.; Ding, Q.-Z.; Guo, B.-L.; Ma, B.-P. Three New Sesquiterpene Glycosides from the Rhizomes of Trillium tschonoskii. Molecules 2017, 22, 1283.

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