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Molecules 2017, 22(5), 781;

Bioactive Natural Products of Marine Sponges from the Genus Hyrtios

Department of Pharmacognosy, Faculty of Pharmacy, Deraya University, Universities Zone, P.O. Box 61111 New Minia City, Minia, Egypt
National Centre for Radiation Research & Technology, Egyptian Atomic Energy Authority, Ahmed El-Zomor St. 3, El-Zohoor Dist., P.O. Box 29 Nasr City, Cairo, Egypt
Department of Pharmacognosy, Faculty of Pharmacy, Minia University, 61519 Minia, Egypt
Department of Chemistry and Center for Integrated Protein Science Munich (CIPSM), Technische Universität München, Lichtenbergstraβe 4, 85748 Garching, Germany
Department of Botany II, Julius-von-Sachs Institute for Biological Sciences, University of Würzburg, Julius-von-Sachs-Platz 3, 97082 Würzburg, Germany
Author to whom correspondence should be addressed.
Academic Editor: Fernando Albericio
Received: 23 March 2017 / Revised: 28 April 2017 / Accepted: 8 May 2017 / Published: 11 May 2017
(This article belongs to the Collection Bioactive Compounds)


Marine sponges are known as a rich source for novel bioactive compounds with valuable pharmacological potential. One of the most predominant sponge genera is Hyrtios, reported to have various species such as Hyrtios erectus, Hyrtios reticulatus, Hyrtios gumminae, Hyrtios communis, and Hyrtios tubulatus and a number of undescribed species. Members of the genus Hyrtios are a rich source of natural products with diverse and valuable biological activities, represented by different chemical classes including alkaloids, sesterterpenes and sesquiterpenes. This review covers the literature until June 2016, providing a complete survey of all compounds isolated from the genus Hyrtios with their corresponding biological activities whenever applicable. View Full-Text
Keywords: bioactive; marine natural products; marine sponges; Hyrtios; alkaloids bioactive; marine natural products; marine sponges; Hyrtios; alkaloids

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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Shady, N.H.; El-Hossary, E.M.; Fouad, M.A.; Gulder, T.A.M.; Kamel, M.S.; Abdelmohsen, U.R. Bioactive Natural Products of Marine Sponges from the Genus Hyrtios. Molecules 2017, 22, 781.

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