Atractylenolide II Inhibits Proliferation, Motility and Induces Apoptosis in Human Gastric Carcinoma Cell Lines HGC-27 and AGS
Abstract
:1. Introduction
2. Results
2.1. AT-II Inhibits Proliferation in HGC-27 and AGS Cells
2.2. AT-II Affects Morphological Changes
2.3. AT-II Induces Apoptosis in HGC-27 and AGS Cells
2.4. AT-II Suppresses the Capability of Cell Motility
2.5. AT-II Regulates the Protein Expression Levels of Bax and Bcl-2
2.6. AT-II Inhibits the Phosphorylation of ERK and Akt in HGC-27 and AGS Cells
3. Discussion
4. Materials and Methods
4.1. Reagents
4.2. Cell Lines and Cell Culture
4.3. Cell Growth Assay
4.4. Cell Morphological Assessment
4.5. Apoptosis Assay
4.6. Wound Healing Assay
4.7. Western Blot Analysis
4.8. Statistical Analysis
Acknowledgments
Author Contributions
Conflicts of Interest
References
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Tian, S.; Yu, H. Atractylenolide II Inhibits Proliferation, Motility and Induces Apoptosis in Human Gastric Carcinoma Cell Lines HGC-27 and AGS. Molecules 2017, 22, 1886. https://doi.org/10.3390/molecules22111886
Tian S, Yu H. Atractylenolide II Inhibits Proliferation, Motility and Induces Apoptosis in Human Gastric Carcinoma Cell Lines HGC-27 and AGS. Molecules. 2017; 22(11):1886. https://doi.org/10.3390/molecules22111886
Chicago/Turabian StyleTian, Shuang, and Hongdan Yu. 2017. "Atractylenolide II Inhibits Proliferation, Motility and Induces Apoptosis in Human Gastric Carcinoma Cell Lines HGC-27 and AGS" Molecules 22, no. 11: 1886. https://doi.org/10.3390/molecules22111886
APA StyleTian, S., & Yu, H. (2017). Atractylenolide II Inhibits Proliferation, Motility and Induces Apoptosis in Human Gastric Carcinoma Cell Lines HGC-27 and AGS. Molecules, 22(11), 1886. https://doi.org/10.3390/molecules22111886