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Molecules 2016, 21(9), 1250;

Two New Clerodane Diterpenes from Tinospora sagittata

College of Plant Protection, Hunan Agricultural University, Changsha 410128, China
Hunan Co-Innovation Center for Utilization of Botanical Functional Ingredients, Changsha 410128, China
State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing 100193, China
Author to whom correspondence should be addressed.
Academic Editor: Derek J. McPhee
Received: 24 August 2016 / Revised: 16 September 2016 / Accepted: 16 September 2016 / Published: 19 September 2016
(This article belongs to the Section Natural Products Chemistry)
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Two new clerodane-type diterpenes, tinosporins C (1) and tinosporins D (2) were isolated from the stems of Tinospora sagittata (Oliv.), together with three known ones, columbin (3), tinophylloloside (4), and tinospinoside D (5). The structures of these compounds were determined on the basis of spectroscopic data interpretation, with that of the absolute configuration of compound 1 was assigned by experimental and calculated ECD spectra. The cytotoxicity and α-glucosidase inhibitory activities of isolated compounds were evaluated in vitro. View Full-Text
Keywords: Tinospora sagittata; clerodane diterpenes; α-glucosidase inhibitory activity Tinospora sagittata; clerodane diterpenes; α-glucosidase inhibitory activity

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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Li, G.; Ding, W.; Wan, F.; Li, Y. Two New Clerodane Diterpenes from Tinospora sagittata. Molecules 2016, 21, 1250.

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