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Molecules 2016, 21(10), 1358;

Methodology for the Construction of the Bicyclo[4.3.0]nonane Core

Department of Chemistry, University of Connecticut, Storrs, CT 06269 USA
Author to whom correspondence should be addressed.
Academic Editor: Vassilios Roussis
Received: 31 July 2016 / Revised: 23 September 2016 / Accepted: 3 October 2016 / Published: 12 October 2016
(This article belongs to the Collection Triterpenes and Triterpenoids)
Full-Text   |   PDF [4312 KB, uploaded 12 October 2016]   |  


The bicyclo[4.3.0]nonane scaffold, commonly known as a hydrindane, is a common structural motif found in many terpenoid structures and one that remains a challenge for synthetic chemists to elaborate with appropriate regio- and stereo-selectivity. Over the course of the study of terpene natural products, the elaboration of the hydrindane structure has seen progress on the utilization of both old and newer methods to achieve the desired outcomes. This review seeks to serve as a general overview of these methods, and detail specific examples. View Full-Text
Keywords: triterpenes; triterpenoids; Diels-Alder; metathesis; Michael additions triterpenes; triterpenoids; Diels-Alder; metathesis; Michael additions

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Eddy, N.A.; Ichalkaranje, P. Methodology for the Construction of the Bicyclo[4.3.0]nonane Core. Molecules 2016, 21, 1358.

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