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Molecules 2015, 20(1), 839-845;

Isoleojaponin, a New Halimane Diterpene Isolated from Leonurus japonicus

College of Chemistry and Chemical Engineering, Anyang Normal University, Anyang 455000, Henan, China
Authors to whom correspondence should be addressed.
Academic Editor: Derek J. McPhee
Received: 6 November 2014 / Accepted: 6 January 2015 / Published: 7 January 2015
(This article belongs to the Section Natural Products Chemistry)
Full-Text   |   PDF [891 KB, uploaded 7 January 2015]   |  


Leojaponin (2), a labdane diterpene, was isolated from the EtOH extract of the herb of Leonurus japonicus together with a new halimane diterpene named isoleojaponin (1). Isoleojaponin has a new diterpene skeleton with a unique cross-conjugated α,β-unsaturated ketone system, Their structures were elucidated by physical and spectroscopic analysis, and the relative configuration of the chiral C-9 carbon was determined by a computational method, and analysis of its possible biogenesis pathways. View Full-Text
Keywords: Leonurus japonicus; labdane diterpenoid; isoleojaponin; halimane Leonurus japonicus; labdane diterpenoid; isoleojaponin; halimane

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Wu, H.; Wang, S.; Xu, Z.; Sun, S.; Liu, H.; Wang, J.; E, Y.; Lv, Y.; Dong, X.; Li, G.; Zhang, L.; Shi, Y. Isoleojaponin, a New Halimane Diterpene Isolated from Leonurus japonicus. Molecules 2015, 20, 839-845.

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