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Molecules 2014, 19(6), 7480-7496;

Regulation of Plant Immunity through Modulation of Phytoalexin Synthesis

Department of Crop Sciences, University of Illinois, 1201 W. Gregory Drive, Urbana, IL 61801, USA
United States Department of Agriculture (USDA), Agricultural Research Service, University of Illinois, 1101 W. Peabody Drive, Urbana, IL 61801, USA
Author to whom correspondence should be addressed.
Received: 15 April 2014 / Revised: 29 May 2014 / Accepted: 30 May 2014 / Published: 6 June 2014
(This article belongs to the Special Issue Phytoalexins: Current Progress and Future Prospects)
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Soybean hairy roots transformed with the resveratrol synthase and resveratrol oxymethyl transferase genes driven by constitutive Arabidopsis actin and CsVMV promoters were characterized. Transformed hairy roots accumulated glycoside conjugates of the stilbenic compound resveratrol and the related compound pterostilbene, which are normally not synthesized by soybean plants. Expression of the non-native stilbenic phytoalexin synthesis in soybean hairy roots increased their resistance to the soybean pathogen Rhizoctonia solani. The expression of the AhRS3 gene resulted in 20% to 50% decreased root necrosis compared to that of untransformed hairy roots. The expression of two genes, the AhRS3 and ROMT, required for pterostilbene synthesis in soybean, resulted in significantly lower root necrosis (ranging from 0% to 7%) in transgenic roots than in untransformed hairy roots that had about 84% necrosis. Overexpression of the soybean prenyltransferase (dimethylallyltransferase) G4DT gene in soybean hairy roots increased accumulation of the native phytoalexin glyceollin resulting in decreased root necrosis. View Full-Text
Keywords: soybean; hairy roots; transformation; phytoalexins; resveratrol; pterostilbene; glyceollins soybean; hairy roots; transformation; phytoalexins; resveratrol; pterostilbene; glyceollins

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Zernova, O.V.; Lygin, A.V.; Pawlowski, M.L.; Hill, C.B.; Hartman, G.L.; Widholm, J.M.; Lozovaya, V.V. Regulation of Plant Immunity through Modulation of Phytoalexin Synthesis. Molecules 2014, 19, 7480-7496.

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