Synthesis of Silver Nanoparticles by Green Method Stabilized to Synthetic Human Stomach Fluid
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Surfactants Research Chair, Department of Chemistry, College of Science, King Saud University, P.O.Box 2455, Riyadh 11451, Saudi Arabia
2
Petroleum Application Department, Egyptian Petroleum Research Institute, Cairo 11727, Egypt
*
Author to whom correspondence should be addressed.
Molecules 2014, 19(5), 6737-6753; https://doi.org/10.3390/molecules19056737
Received: 22 April 2014
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Revised: 20 May 2014
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Accepted: 21 May 2014
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Published: 23 May 2014
(This article belongs to the Collection Bioactive Compounds)
Silver nanoparticles (Ag NP) have been attracted much attention in recent years in biomedical applications due to their antimicrobial activity, but their drawbacks include toxicity and instability to aqueous hydrochloric acid solutions. Ag NPs have now been successfully prepared by a simple and “green” synthesis method by reducing Ag+ ions in the presence of modified poly(vinyl alcohol) thiol (PVA-SH) in aqueous acidic solution. In this respect, Ag NPs were stabilized by coating different types of citrate-reduced Ag NPs with different weight ratios (1–3 Wt. %) of PVSH derivatives. The as-prepared Ag NPs were characterized using UV-Visible, high resolution transmission electron microscopy/ energy dispersive X-ray spectroscopy (TEM/EDS), dynamic light scattering (DLS) and X-ray powder diffraction (XRD) combined with Rietveld analysis. The changes in size, shape, and hydrodynamic diameter of Ag NPs after different duration exposure to synthetic stomach fluid (SSF) and1 M HCl were determined using TEM, XRD and UV-Visible analyses. The data indicated that these Ag NPs possessed high stability to SSF for more than 90 days, which was not previously reported in the literature.
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Keywords:
silver nanoparticles; poly(vinyl alcohol)thiol; aqueous acidic solution; citrate reducing agent
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MDPI and ACS Style
Atta, A.M.; Al-Lohedan, H.A.; Ezzat, A.O. Synthesis of Silver Nanoparticles by Green Method Stabilized to Synthetic Human Stomach Fluid. Molecules 2014, 19, 6737-6753. https://doi.org/10.3390/molecules19056737
AMA Style
Atta AM, Al-Lohedan HA, Ezzat AO. Synthesis of Silver Nanoparticles by Green Method Stabilized to Synthetic Human Stomach Fluid. Molecules. 2014; 19(5):6737-6753. https://doi.org/10.3390/molecules19056737
Chicago/Turabian StyleAtta, Ayman M., Hamad A. Al-Lohedan, and Abdelrahman O. Ezzat. 2014. "Synthesis of Silver Nanoparticles by Green Method Stabilized to Synthetic Human Stomach Fluid" Molecules 19, no. 5: 6737-6753. https://doi.org/10.3390/molecules19056737
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