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Molecules 2013, 18(8), 9663-9669;

Three Novel Xanthones from Garcinia paucinervis and Their Anti-TMV Activity

Yunnan Academy of Tobacco Agricultural Sciences, Yuxi 653100, China
Key Laboratory of Tobacco Chemistry of Yunnan Province, Yunnan Academy of Tobacco Science, Kunming 650106, China
Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission and Ministry of Education, Yunnan University of Nationalities, Kunming 650031, China
Authors to whom correspondence should be addressed.
Received: 6 June 2013 / Revised: 2 August 2013 / Accepted: 5 August 2013 / Published: 13 August 2013
(This article belongs to the Section Natural Products Chemistry)
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Phytochemical investigations of the leaves of Garcinia paucinervis resulted in the isolation of three new xanthones 13 and five known analogues 48. Structural elucidations of 13 were performed by spectral methods such as 1D and 2D (HMQC, HMBC, and ROESY) NMR spectroscopy, in addition to high resolution mass spectrometry. Compounds 13 showed anti-TMV activities, with inhibition rates above 20%, especially for 1, which had a lower IC50 value of 21.4 µM. View Full-Text
Keywords: Garcinia paucinervis; xanthones; anti-tobacco mosaic virus Garcinia paucinervis; xanthones; anti-tobacco mosaic virus

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Wu, Y.-P.; Zhao, W.; Xia, Z.-Y.; Kong, G.-H.; Lu, X.-P.; Hu, Q.-F.; Gao, X.-M. Three Novel Xanthones from Garcinia paucinervis and Their Anti-TMV Activity. Molecules 2013, 18, 9663-9669.

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