Next Article in Journal
Naucline, a New Indole Alkaloid from the Bark of Nauclea officinalis
Next Article in Special Issue
Ionic Liquid Applications in Peptide Chemistry: Synthesis, Purification and Analytical Characterization Processes
Previous Article in Journal
Essential Oils in Combination and Their Antimicrobial Properties
Previous Article in Special Issue
Coupling of Nanoporous Chromium, Aluminium-Containing Silicates with an Ionic Liquid for the Transformation of Glucose into 5-(Hydroxymethyl)-2-furaldehyde
Open AccessArticle

A Simple Halide-to-Anion Exchange Method for Heteroaromatic Salts and Ionic Liquids

Laboratory of Organic Chemistry, Faculty of Pharmacy, University of Barcelona, Joan XXIII s/n, 08028 Barcelona, Spain
*
Authors to whom correspondence should be addressed.
Molecules 2012, 17(4), 4007-4027; https://doi.org/10.3390/molecules17044007
Received: 29 February 2012 / Revised: 20 March 2012 / Accepted: 23 March 2012 / Published: 2 April 2012
(This article belongs to the Collection Ionic Liquids)
A broad and simple method permitted halide ions in quaternary heteroaromatic and ammonium salts to be exchanged for a variety of anions using an anion exchange resin (A form) in non-aqueous media. The anion loading of the AER (OH form) was examined using two different anion sources, acids or ammonium salts, and changing the polarity of the solvents. The AER (A form) method in organic solvents was then applied to several quaternary heteroaromatic salts and ILs, and the anion exchange proceeded in excellent to quantitative yields, concomitantly removing halide impurities. Relying on the hydrophobicity of the targeted ion pair for the counteranion swap, organic solvents with variable polarity were used, such as CH3OH, CH3CN and the dipolar nonhydroxylic solvent mixture CH3CN:CH2Cl2 (3:7) and the anion exchange was equally successful with both lipophilic cations and anions. View Full-Text
Keywords: imidazolium salts; pyridinium salts; ammonium salts; anion exchange resin; counteranion exchange; ionic liquids imidazolium salts; pyridinium salts; ammonium salts; anion exchange resin; counteranion exchange; ionic liquids
Show Figures

Graphical abstract

MDPI and ACS Style

Alcalde, E.; Dinarès, I.; Ibáñez, A.; Mesquida, N. A Simple Halide-to-Anion Exchange Method for Heteroaromatic Salts and Ionic Liquids. Molecules 2012, 17, 4007-4027.

Show more citation formats Show less citations formats

Article Access Map by Country/Region

1
Only visits after 24 November 2015 are recorded.
Back to TopTop