Next Article in Journal
Enrichment and Purification of Deoxyschizandrin and γ-Schizandrin from the Extract of Schisandra chinensis Fruit by Macroporous Resins
Previous Article in Journal
Synthesis and Preliminary Investigations of the siRNA Delivery Potential of Novel, Single-Chain Rigid Cationic Carotenoid Lipids
Article Menu

Export Article

Open AccessArticle
Molecules 2012, 17(3), 3501-3509;

Synthesis and Structural Determination of Novel 5-Arylidene-3-N(2-alkyloxyaryl)-2-thioxothiazolidin-4-ones

Laboratoire de Synthèse Organique Appliquée, BP 1524, El Menaouer, Université d’Oran Es-Senia, 31000 Oran, Algérie
Laboratoire de Structure, Elaboration et Applications des Matériaux Moléculaires (SEA2M), Département de Génie des Procédés, Faculté des Sciences et de la Technologie, Université de Mostaganem, 27000 Mostaganem, Algérie
Author to whom correspondence should be addressed.
Received: 5 January 2012 / Revised: 26 February 2012 / Accepted: 1 March 2012 / Published: 19 March 2012
Full-Text   |   PDF [241 KB, uploaded 18 June 2014]   |  


As part of our project devoted to the synthesis of heterocycles including thiazole rings, some new 5-arylidene-2-thioxo-3-N-arylthiazolidin-4-ones were synthesized by Knoevenagel condensation. An interesting feature of these compounds is that their chirality is induced by that of their 3-N-(2-alkyloxyaryl)-2-thioxothiazolidin-4-one precursors, which in turn is due to the presence of a C2 axis of chirality. These new compounds were characterized by spectroscopic methods (IR, 1H-NMR, 13C-NMR). The structure of compound (Z)-(2g) was further determined by X-ray diffraction. View Full-Text
Keywords: N-arylthiazolidin-4-one; (Z)-5-arylidene-3-N-arylthiazolidin-4-one; chirality; IR; 1H-NMR; 13C-NMR; X-ray diffraction; nonlinear optical properties; solar cells N-arylthiazolidin-4-one; (Z)-5-arylidene-3-N-arylthiazolidin-4-one; chirality; IR; 1H-NMR; 13C-NMR; X-ray diffraction; nonlinear optical properties; solar cells

Graphical abstract

This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Share & Cite This Article

MDPI and ACS Style

Toubal, K.; Djafri, A.; Chouaih, A.; Talbi, A. Synthesis and Structural Determination of Novel 5-Arylidene-3-N(2-alkyloxyaryl)-2-thioxothiazolidin-4-ones. Molecules 2012, 17, 3501-3509.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics



[Return to top]
Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top