Molecules 2011, 16(4), 3168-3178; https://doi.org/10.3390/molecules16043168
Syntheses, Structures and Antimicrobial Activities of bis(Imino)acenaphthene (BIAN) Imidazolium Salts
1
Department of Chemistry and Biochemistry, University of Texas at Austin, 1 University Station, A5300, Austin, TX 78712, USA
2
Chemistry Department, College of Science, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia
*
Author to whom correspondence should be addressed.
Received: 25 March 2011 / Revised: 11 April 2011 / Accepted: 12 April 2011 / Published: 15 April 2011
Abstract
The syntheses of four new bis(imino)acenaphthene (BIAN) imidazolium chlorides are reported, three of which have been structurally characterized. The synthesis of a new, structurally authenticated BIAN ligand is also described. We report the results of the use of these BIAN imidazolium salts as antimicrobials against the pathogens S. aureus, B. subtilis, E. coli and P. aeruginosa. The antimicrobial efficacies were particularly high for the N-(2,6-diisopropylphenyl)- and N-(mesityl)- substituted BIAN imidazolium salts (MIC values < 0.6 μg/mL). View Full-TextKeywords:
imidazolium chloride; BIAN; synthesis; X-ray structure; antimicrobial activity
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Butorac, R.R.; Al-Deyab, S.S.; Cowley, A.H. Syntheses, Structures and Antimicrobial Activities of bis(Imino)acenaphthene (BIAN) Imidazolium Salts. Molecules 2011, 16, 3168-3178.
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