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Molecules 2011, 16(10), 8646-8653;

Two New Epoxysteroids from Helianthus tuberosus

Yantai Institute of Coastal Zone Research, Chinese Academy of Sciences, Yantai 264003, China
Author to whom correspondence should be addressed.
Received: 5 September 2011 / Revised: 10 October 2011 / Accepted: 11 October 2011 / Published: 13 October 2011
(This article belongs to the Special Issue Steroids)
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Two new epoxy steroids, 5α,8α-epidioxy-22β,23β-epoxyergosta-6-en-3β-ol (1) and 5α,8α-epidioxy-22α,23α-epoxyergosta-6-en-3β-ol (2), and ten known steroids including (24R)-5α,8α-epidioxyergosta-6-en-3β-ol (3), (22E,24R)-5α,8α-epidioxyergosta-6,22-dien-3β-ol (4), (22E,24R)-5α,8α-epidioxyergosta-6,9(11),22-trien-3β-ol (5), β-sitosterol (6), sitost-5-en-3β-ol acetate (7), 7α-hydroxysitosterol (8), schleicheol 2 (9), (24R)-24-ethyl-5α-cholestane-3β,5α,6β-triol (10), 7α-hydroxystigmasterol (11), and stigmasterol (12) were isolated from Helianthus tuberosus grown in Laizhou salinized land of coastal zone of Bohai Sea, China. The structures of these compounds were unambiguously established by 1D, 2D NMR and mass spectroscopic techniques. The new compounds 1 and 2 exhibited weak antibacterial activity and no antifungal activity. View Full-Text
Keywords: Helianthus tuberosus; steroid; 5α,8α-epidioxy-22β,23β-epoxyergosta-6-en-3β-ol; 5α,8α-epidioxy-22α,23α-epoxyergosta-6-en-3β-ol Helianthus tuberosus; steroid; 5α,8α-epidioxy-22β,23β-epoxyergosta-6-en-3β-ol; 5α,8α-epidioxy-22α,23α-epoxyergosta-6-en-3β-ol

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Li, X.-D.; Miao, F.-P.; Ji, N.-Y. Two New Epoxysteroids from Helianthus tuberosus. Molecules 2011, 16, 8646-8653.

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