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Open AccessCommunication

Efficient and Eco-Friendly Preparation of 4-Methyl-5-formyl-thiazole

The Key Laboratory of Bioorganic Phosphorous Chemistry and Chemical Biology, Department of Chemistry, Tsinghua University, Beijing 100084, P.R. China
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Molecules 2008, 13(4), 943-947; https://doi.org/10.3390/molecules13040943
Received: 6 April 2008 / Revised: 17 April 2008 / Accepted: 17 April 2008 / Published: 21 April 2008
4-Methyl-5-formylthiazole, an intermediate for synthesizing cefditoren pivoxil,was prepared in good yield by Pd/BaSO4 catalyzed hydrogenation of 4-methylthiazole-5-carboxylic acid chloride. Detailed reaction conditions have been studied. View Full-Text
Keywords: 4-Methyl-5-formylthiazole; Pd/BaSO4 catalyzed hydrogenation. 4-Methyl-5-formylthiazole; Pd/BaSO4 catalyzed hydrogenation.
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Bai, N.; Sha, Y.; Meng, G. Efficient and Eco-Friendly Preparation of 4-Methyl-5-formyl-thiazole. Molecules 2008, 13, 943-947.

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