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Review

Thermophoretic Micron-Scale Devices: Practical Approach and Review

by 1,† and 1,2,*,†
1
Institute of Biological Information Processing (IBI-4: Biomacromolecular Systems and Processes) & JARA-SOFT, Forschungszentrum Jülich GmbH, D-52428 Jülich, Germany
2
Department für Chemie—Physikalische Chemie, Universität zu Köln, 50939 Cologne, Germany
*
Author to whom correspondence should be addressed.
These authors contributed equally to this work.
Entropy 2020, 22(9), 950; https://doi.org/10.3390/e22090950
Received: 29 June 2020 / Revised: 18 August 2020 / Accepted: 25 August 2020 / Published: 28 August 2020
(This article belongs to the Special Issue Review Papers for Entropy)
In recent years, there has been increasing interest in the development of micron-scale devices utilizing thermal gradients to manipulate molecules and colloids, and to measure their thermophoretic properties quantitatively. Various devices have been realized, such as on-chip implements, micro-thermogravitational columns and other micron-scale thermophoretic cells. The advantage of the miniaturized devices lies in the reduced sample volume. Often, a direct observation of particles using various microscopic techniques is possible. On the other hand, the small dimensions lead to some technical problems, such as a precise temperature measurement on small length scale with high spatial resolution. In this review, we will focus on the “state of the art” thermophoretic micron-scale devices, covering various aspects such as generating temperature gradients, temperature measurement, and the analysis of the current micron-scale devices. We want to give researchers an orientation for their development of thermophoretic micron-scale devices for biological, chemical, analytical, and medical applications. View Full-Text
Keywords: microfluidic; thermophoresis; thermodiffusion; temperature gradients; temperature measurements microfluidic; thermophoresis; thermodiffusion; temperature gradients; temperature measurements
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MDPI and ACS Style

Lee, N.; Wiegand, S. Thermophoretic Micron-Scale Devices: Practical Approach and Review. Entropy 2020, 22, 950. https://doi.org/10.3390/e22090950

AMA Style

Lee N, Wiegand S. Thermophoretic Micron-Scale Devices: Practical Approach and Review. Entropy. 2020; 22(9):950. https://doi.org/10.3390/e22090950

Chicago/Turabian Style

Lee, Namkyu, and Simone Wiegand. 2020. "Thermophoretic Micron-Scale Devices: Practical Approach and Review" Entropy 22, no. 9: 950. https://doi.org/10.3390/e22090950

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