Announcements

MDPI is delighted to announce the establishment of the Michele Parrinello Award. Named in honor of Professor Michele Parrinello, the award celebrates his exceptional contributions and his profound impact on the field of computational physical science research.

The award will be presented biennially to distinguished scientists who have made outstanding achievements and contributions in the field of computational physical science—spanning physics, chemistry, and materials science.

About Professor Michele Parrinello

"Do not be afraid of new things. I see it many times when we discuss a new thing that young people are scared to go against the mainstream a little bit, thinking what is going to happen to me and so on. Be confident that what you do is meaningful, and do not be afraid, do not listen too much to what other people have to say.”

——Professor Michele Parrinello

Born in Messina in 1945, he received his degree from the University of Bologna and is currently affiliated with the Italian Institute of Technology. Professor Parrinello is known for his many technical innovations in the field of atomistic simulations and for a wealth of interdisciplinary applications ranging from materials science to chemistry and biology. Together with Roberto Car, he introduced ab initio molecular dynamics, also known as the Car–Parrinello method, marking the beginning of a new era both in the area of electronic structure calculations and in molecular dynamics simulations. He is also known for the Parrinello–Rahman method, which allows crystalline phase transitions to be studied by molecular dynamics. More recently, he has introduced metadynamics for the study of rare events and the calculation of free energies.

For his work, he has been awarded many prizes and honorary degrees. He is a member of numerous academies and learned societies, including the German Berlin-Brandenburgische Akademie der Wissenschaften, the British Royal Society, and the Italian Accademia Nazionale dei Lincei, which is the major academy in his home country of Italy.

Award Committee

The award committee will be chaired by Professor Xin-Gao Gong, a computational condensed matter physicist, academician of the Chinese Academy of Sciences, and professor at the Department of Physics, Fudan University. Professor Xin-Gao Gong will lead a panel of several senior experts in the field to oversee the evaluation and selection process. The Institute for Computational Physical Sciences at Fudan University (Shanghai, China), led by Professor Xin-Gao Gong, will serve as the supporting institute for the award.

"We hope the Michele Parrinello Award will recognize scientists who have made significant contributions to the field of computational condensed matter physics and at the same time set a benchmark for the younger generation, providing clear direction for their pursuit—this is precisely the original intention behind establishing the award."

——Professor Xin-Gao Gong

The first edition of the award was officially launched on 1 November 2025. Nominations will be accepted before the end of March 2026. For further details, please visit mparrinelloaward.org.

About the MDPI Sustainability Foundation and MDPI Awards

The Michele Parrinello Award is part of the MDPI Sustainability Foundation, which is dedicated to advancing sustainable development through scientific progress and global collaboration. The foundation also oversees the World Sustainability Award, the Emerging Sustainability Leader Award, and the Tu Youyou Award. The establishment of the Michele Parrinello Award will further enrich the existing award portfolio, providing continued and diversified financial support to outstanding professionals across various fields. 

In addition to these foundation-level awards, MDPI journals also recognize outstanding contributions through a range of honors, including Best Paper Awards, Outstanding Reviewer Awards, Young Investigator Awards, Travel Awards, Best PhD Thesis Awards, Editor of Distinction Awards, and others. These initiatives aim to recognize excellence across disciplines and career stages, contributing to the long-term vitality and sustainability of scientific research.

Find more information on awards here.

We are honored to recognize the 2024 MDPI Top 1000 Reviewers—scholars whose exemplary commitment to rigorous and constructive peer review is vital in upholding the highest standards of academic publishing.

Selected from a distinguished pool of 215,000 reviewers from 65 countries and regions worldwide, these honorees stand out for their exceptional expertise, diligence, and dedication to advancing research through timely and thoughtful reviews. Their constructive and impartial feedback ensures the publication of high-quality, impactful research, while their timely reviews facilitate swift revisions and faster publication of innovative work.

Peer review is the invisible foundation of academic progress. With gratitude and respect, we celebrate these 1000 scholars who made that foundation stronger in 2024. We respected all privacy preferences, with part of nominees opting for limited attribution.

The names of these reviewers are listed below in alphabetical order by first name:

We are delighted to share with you 9 reprints of Special Issues published in 2024–2025 in Biomolecules (ISSN: 2218-273X). They were selected by the Biomolecules Editorial Office, and each has ten or more articles published. You can read more reprints of the Special Issues published by Biomolecules here: https://www.mdpi.com/journal/biomolecules/special_issues.

	1. “Computational Analysis and Conformational Modeling for Protein Structure and Interaction” Guest Editors: Clement Agoni and Clement Agoni ISBN 978-3-7258-5825-5 (Hardback), ISBN 978-3-7258-5826-2 (PDF) https://doi.org/10.3390/books978-3-7258-5826-2 Available online: https://www.mdpi.com/books/reprint/11948-computational-analysis-and-conformational-modeling-for-protein-structure-and-interaction
	2. “Bioactive Molecules Structures, Functions and Potential Uses for Cancer Prevention and Targeted Therapies (2nd Edition)” Guest Editor: Q. Ping Dou ISBN 978-3-7258-5965-8 (Hardback), ISBN 978-3-7258-5966-5 (PDF) https://doi.org/10.3390/books978-3-7258-5966-5 Available online: https://www.mdpi.com/books/reprint/11945-bioactive-molecules
	3. “Peroxisome Proliferator-Activated Receptors (PPARs) A Themed Issue in Honor of Prof. Walter Wahli” Guest Editors: Hervé Guillou and Manuel Vázquez-Carrera ISBN 978-3-7258-5529-2 (Hardback), ISBN 978-3-7258-5530-8 (PDF) https://doi.org/10.3390/books978-3-7258-5530-8 Available online:  https://www.mdpi.com/books/reprint/11890-peroxisome-proliferator-activated-receptors-ppars
	4. “Zinc in Health and Disease Conditions” Guest Editor: Xiang-Ping Chu ISBN 978-3-7258-4143-1 (Hardback), ISBN 978-3-7258-4144-8 (PDF) https://doi.org/10.3390/books978-3-7258-4144-8 Available online:  https://www.mdpi.com/books/reprint/11326-zinc-in-health-and-disease-conditions
	5. “Development, Characterization, and Application of Bioactive Peptides, Diagnostic Biomarkers, and Pharmaceutical Proteins” Guest Editors: Hyung-Sik Won and Ji-Hun Kim ISBN 978-3-7258-3564-5 (Hardback), ISBN 978-3-7258-3563-8 (PDF) https://doi.org/10.3390/books978-3-7258-3563-8 Available online:  https://www.mdpi.com/books/reprint/10685-development-characterization-and-application-of-bioactive-peptides-diagnostic-biomarkers-and
	6. “Ribosomal Proteins in Ribosome Assembly” Guest Editors: Brigitte Pertschy and Ingrid Zierler ISBN 978-3-7258-3218-7 (Hardback), ISBN 978-3-7258-3217-0 (PDF) https://doi.org/10.3390/books978-3-7258-3217-0 Available online:  https://www.mdpi.com/books/reprint/10483-ribosomal-proteins-in-ribosome-assembly
	7. “Cell Differentiation, Oxidative Stress, and Oxygen Radicals—in Honor of Prof. Michael Breitenbach” Guest Editors: Mark Rinnerthaler and Markus Ralser ISBN 978-3-7258-2616-2 (Hardback), ISBN 978-3-7258-2615-5 (PDF) https://doi.org/10.3390/books978-3-7258-2615-5 Available online: https://www.mdpi.com/books/reprint/10259-cell-differentiation-oxidative-stress-and-oxygen-radicals-in-honor-of-prof-michael-breitenbach
	8. “Versatility of Glutathione Transferase Proteins” Guest Editor: Bengt Mannervik ISBN 978-3-7258-0453-5 (Hardback), ISBN 978-3-7258-0454-2 (PDF) https://doi.org/10.3390/books978-3-7258-0454-2 Available online:  https://www.mdpi.com/books/reprint/8931-versatility-of-glutathione-transferase-proteins
	9. “Biomarkers of Oxidative and Radical Stress” Guest Editor: Chryssostomos Chatgilialoglu ISBN 978-3-7258-0328-6 (Hardback), ISBN 978-3-7258-0327-9 (PDF) https://doi.org/10.3390/books978-3-7258-0327-9 Available online:  https://www.mdpi.com/books/reprint/8864-biomarkers-of-oxidative-and-radical-stress

We are pleased to announce updates to our article template, aimed at improving the readability and visual appeal of our publications. The following updates will be applied to articles published in volumes in 2026, starting from 19 December 2025.

Left information bar:

• Updated the logo and URL for “Check for updates”;
• Removed the “Citation” section (Note: Citation details remain accessible via “Cite” in the online article version);
• Changed the link in “Copyright” to a hyperlink format.

Footer:

• Added a DOI link at the bottom-right corner of each page.

The updated template is now available for download from the Instructions for Authors page of each journal.

We hope that the new version of the template will provide users with better experience and make the process more convenient.

For any questions or suggestions, please contact our production team at production@mdpi.com.

We are delighted to share a collection of highly viewed papers and successful Special Issues on bioinformatics and systems biology that were published in Biomolecules (ISSN: 2218-273X) in 2025. The following is a list of articles and Special Issues that we believe may be of interest to you:

Articles:

“Structure-Based Approaches for Protein–Protein Interaction Prediction Using Machine Learning and Deep Learning”
by Despoina P. Kiouri, Georgios C. Batsis and Christos T. Chasapis
Biomolecules 2025, 15(1), 141; https://doi.org/10.3390/biom15010141
Available online: https://www.mdpi.com/2218-273X/15/1/141

“Transcriptomic Analysis Corroborates the New Radial Model of the Mouse Pallial Amygdala”
by Gloria Fernández, Lara López-González, Eduardo Pons-Fuster, Luis Puelles and Elena Garcia-Calero
Biomolecules 2025, 15(8), 1160; https://doi.org/10.3390/biom15081160
Available online: https://www.mdpi.com/2218-273X/15/8/1160

“Unraveling the Engagement of Kinases to CRBN Through a Shared Structural Motif to Optimize PROTACs Efficacy”
by Serena Rosignoli, Sara Giordani, Maddalena Pacelli, Giulia Guarguaglini and Alessandro Paiardini
Biomolecules 2025, 15(2), 206; https://doi.org/10.3390/biom15020206
Available online: https://www.mdpi.com/2218-273X/15/2/206

“Conditioned Generative Modeling of Molecular Glues: A Realistic AI Approach for Synthesizable Drug-like Molecules”
by Naeyma N. Islam and Thomas R. Caulfield
Biomolecules 2025, 15(6), 849; https://doi.org/10.3390/biom15060849
Available online: https://www.mdpi.com/2218-273X/15/6/849

“Challenges and Opportunities in Quantifying Bioactive Compounds in Human Breastmilk”
by Amna Ghith, Reza Maleki, Luke E. Grzeskowiak, Lisa H. Amir and Wendy V. Ingman
Biomolecules 2025, 15(3), 325; https://doi.org/10.3390/biom15030325
Available online: https://www.mdpi.com/2218-273X/15/3/325

“Overview of Proteomic Analysis of Amyloid Plaques and Neurofibrillary Tangles in Alzheimer’s Disease”
by Amber Grewal, Simran Raikundalia, Joseph Zaia and Manveen K. Sethi
Biomolecules 2025, 15(9), 1310; https://doi.org/10.3390/biom15091310
Available online: https://www.mdpi.com/2218-273X/15/9/1310

“Real-World Analysis of HRD Assay Variability in High-Grade Serous Ovarian Cancer: Impacts of BRCA1/2 Mutation Subtypes on HRD Assessment”
by Giovanni Luca Scaglione, Valentina Lombardo, Maurizio Polano, Giuseppa Scandurra, Angela Pettinato, Corrado Giunta, Rosario Iemmolo, Paolo Scollo and Ettore D. Capoluongo
Biomolecules 2025, 15(5), 745; https://doi.org/10.3390/biom15050745
Available online: https://www.mdpi.com/2218-273X/15/5/745

“Omics Investigations of Prostate Cancer Cells Exposed to Simulated Microgravity Conditions”
by Herbert Schulz, Fatima Abdelfattah, Anna Heinrich, Daniela Melnik, Viviann Sandt, Marcus Krüger, Markus Wehland, Per Hoffmann, José Luis Cortés-Sánchez, Matthias Evert et al.
Biomolecules 2025, 15(2), 303; https://doi.org/10.3390/biom15020303
Available online: https://www.mdpi.com/2218-273X/15/2/303

“A Map of the Lipid–Metabolite–Protein Network to Aid Multi-Omics Integration”
by Uchenna Alex Anyaegbunam, Aimilia-Christina Vagiona, Vincent ten Cate, Katrin Bauer, Thierry Schmidlin, Ute Distler, Stefan Tenzer, Elisa Araldi, Laura Bindila, Philipp Wild et al.
Biomolecules 2025, 15(4), 484; https://doi.org/10.3390/biom15040484
Available online: https://www.mdpi.com/2218-273X/15/4/484

“Prediction of circRNA–Disease Associations via Graph Isomorphism Transformer and Dual-Stream Neural Predictor”
by Hongchan Li, Yuchao Qian, Zhongchuan Sun and Haodong Zhu
Biomolecules 2025, 15(2), 234; https://doi.org/10.3390/biom15020234
Available online: https://www.mdpi.com/2218-273X/15/2/234

Special Issues:

“Advances in Neuroproteomics”
Guest Editors: Dr. Kenneth R. Williams and Prof. Dr. Angus C. Nairn
Published papers: 10
Viewed by 31385+

“In Silico Drug Design and Discovery: Big Data for Small Molecule Design 2nd Edition”
Guest Editors: Dr. Carmen Cerchia and Prof. Dr. Antonio Lavecchia
Published papers: 7
Viewed by 18055+

“Unveiling Protein Functions, Dynamics and Interactions in Health and Disease Using Experimental and Theoretical Approaches”
Guest Editors: Dr. Daniele Di Marino, Dr. Cristina Maracci, Dr. Alice Romagnoli and Dr. Stefano Motta
Published papers: 9
Viewed by 41810+

“Artificial Intelligence (AI) in Biomedicine”
Guest Editor: Dr. Le Nguyen Quoc Khanh
Published papers: 14
Viewed by 50015+

“Artificial Intelligence (AI) in Biomedicine”
Guest Editor: Dr. Le Nguyen Quoc Khanh
Published papers: 14
Viewed by 50015+

We are delighted to share a collection of highly viewed papers and successful Special Issues on molecular medicine that were published in Biomolecules (ISSN: 2218-273X) in 2025. The following is a list of articles and Special Issues that we believe may be of interest to you:

Articles:

“Weight Reduction with GLP-1 Agonists and Paths for Discontinuation While Maintaining Weight Loss”
by Allison B. Reiss, Shelly Gulkarov, Raymond Lau, Stanislaw P. Klek, Ankita Srivastava, Heather A. Renna and Joshua De Leon
Biomolecules 2025, 15(3), 408; https://doi.org/10.3390/biom15030408
Available online: https://www.mdpi.com/2218-273X/15/3/408

“Retatrutide—A Game Changer in Obesity Pharmacotherapy”
by Vasiliki Katsi, Georgios Koutsopoulos, Christos Fragoulis, Kyriakos Dimitriadis and Konstantinos Tsioufis
Biomolecules 2025, 15(6), 796; https://doi.org/10.3390/biom15060796
Available online: https://www.mdpi.com/2218-273X/15/6/796

“From Cardiovascular-Kidney-Metabolic Syndrome to Cardiovascular-Renal-Hepatic-Metabolic Syndrome: Proposing an Expanded Framework”
by Nikolaos Theodorakis and Maria Nikolaou
Biomolecules 2025, 15(2), 213; https://doi.org/10.3390/biom15020213
Available online: https://www.mdpi.com/2218-273X/15/2/213

“Probiotics and Diet in Rosacea: Current Evidence and Future Perspectives”
by Marco Manfredini, Michele Barbieri, Margherita Milandri and Caterina Longo
Biomolecules 2025, 15(3), 411; https://doi.org/10.3390/biom15030411
Available online: https://www.mdpi.com/2218-273X/15/3/411

“Butyrate Supplementation Improves Intestinal Health and Growth Performance in Livestock: A Review”
by Wenting Chen, Qingshan Ma, Yan Li, Lin Wei, Zhenwei Zhang, Adnan Khan, Muhammad Zahoor Khan and Changfa Wang
Biomolecules 2025, 15(1), 85; https://doi.org/10.3390/biom15010085
Available online: https://www.mdpi.com/2218-273X/15/1/85

“Elevated Kappa Index in the Absence of Cerebrospinal Fluid IgG Oligoclonal Bands: Contribution of Intrathecal IgM and IgA Synthesis”
by Krzysztof Smolik, Roberta Bedin, Patrizia Natali, Martina Cardi, Diego Franciotta, Anna Maria Simone, Paolo Immovilli, Mario Santangelo, Matteo Gastaldi, Giulia De Napoli et al.
Biomolecules 2025, 15(1), 90; https://doi.org/10.3390/biom15010090
Available online: https://www.mdpi.com/2218-273X/15/1/90

“Genes, Cognition, and Their Interplay in Methamphetamine Use Disorder”
by Ramisha Khan, Alyna Turner, Michael Berk, Ken Walder, Susan Rossell, Alexandre A. Guerin and Jee Hyun Kim
Biomolecules 2025, 15(2), 306; https://doi.org/10.3390/biom15020306
Available online: https://www.mdpi.com/2218-273X/15/2/306

“Drug Advances in NAFLD: Individual and Combination Treatment Strategies of Natural Products and Small-Synthetic-Molecule Drugs”
by Xing Wan, Jingyuan Ma, He Bai, Xuyang Hu, Yanna Ma, Mingjian Zhao, Jifeng Liu and Zhijun Duan
Biomolecules 2025, 15(1), 140; https://doi.org/10.3390/biom15010140
Available online: https://www.mdpi.com/2218-273X/15/1/140

“Deep Thought on the HIV Cured Cases: Where Have We Been and What Lies Ahead?”
by Qing Xiao, Sanxiu He, Chaoyu Wang, Yixing Zhou, Chensi Zeng, Jun Liu, Tingting Liu, Tingting Li, Xi Quan, Linyue Wang et al.
Biomolecules 2025, 15(3), 378; https://doi.org/10.3390/biom15030378
Available online: https://www.mdpi.com/2218-273X/15/3/378

“Acral Melanoma: A Review of Its Pathogenesis, Progression, and Management”
by Soo Hyun Kim and Hensin Tsao
Biomolecules 2025, 15(1), 120; https://doi.org/10.3390/biom15010120
Available online: https://www.mdpi.com/2218-273X/15/1/120

Special Issues:

“Cellular and Molecular Mechanisms in Cardiopathy and Therapeutic Strategies”
Guest Editors: Dr. Ying-Hsi Lin and Dr. Shengjie Lu
Published papers: 8
Viewed by 9075+

“New Insights into Kidney Disease Development and Therapy Strategies”
Guest Editors: Dr. José I. López and Dr. Claudia Manini
Published papers: 7
Viewed by 17765+

“Inositol Phosphates in Health and Disease, 2nd Edition”
Guest Editors: Dr. Ivana Vucenik and Prof. Dr. Abulkalam M. Shamsuddin
Published papers: 7
Viewed by 22890+

“Chronic Heart Failure: From Molecular Mechanisms to Therapies Strategies”
Guest Editors: Dr. Josep Comín-Colet and Dr. Marta Tajes
Published papers: 9
Viewed by 14395+

“Nutrition, Metabolism, and Obesity: Novel Strategies and Molecular Mechanisms—Future Perspectives”
Guest Editor: Dr. Marion Korach-André
Published papers: 9
Viewed by 45310+

“Novel Insights into Autoimmune/Autoinflammatory Skin Diseases”
Guest Editors: Prof. Dr. Angelo Valerio Marzano, Prof. Dr. Sergio Crovella and Dr. Chiara Moltrasio
Published papers: 9
Viewed by 29895+

“State of the Art and Perspectives in Antimicrobial Peptides”
Guest Editor: Prof. Dr. Annarita Falanga
Published papers: 9
Viewed by 17930+

“Diabetes, Overweight and Obesity: From Molecular Mechanisms to Therapies Strategies”
Guest Editors: Dr. Othmar Moser and Dr. Harald Sourij
Published papers: 9
Viewed by 47510+

“Biomolecules and Materials Based Approaches in Biomedical Field: 2nd Edition”
Guest Editors: Dr. Sabrina Morelli, Dr. Antonella Piscioneri, Prof. Dr. Chien-Chung Chen and Dr. Loredana De Bartolo
Published papers: 8
Viewed by 18025+

“Tissue Calcification in Normal and Pathological Environments”
Guest Editor: Dr. Fulvia Ortolani
Published papers: 9
Viewed by 26045+

“New Insights into Mechanisms and Therapeutics for Cardiovascular Disorders”
Guest Editors: Prof. Dr. Mohsin Saleet Jafri, Prof. Dr. Carola Yvette Förster and Dr. Tarun W. Dasari
Published papers: 10
Viewed by 33070+

“New Insights into Cardiometabolic Diseases”
Guest Editors: Prof. Dr. Gundu H. R. Rao and Dr. Undurti N. Das
Published papers: 18
Viewed by 83295+

“Pathogenesis and Potential Treatments of Neurointestinal Diseases”
Guest Editors: Dr. Jaime Belkind-Gerson and Dr. Ryo Hotta
Published papers: 13
Viewed by 47980+

“Advances in Biomarkers for Neurodegenerative Diseases”
Guest Editor: Dr. Gessica Sala
Published papers: 12
Viewed by 50315+

We are delighted to share a collection of highly viewed papers and successful Special Issues on cellular biochemistry that were published in Biomolecules (ISSN: 2218-273X) in 2025. The following is a list of articles and Special Issues that we believe may be of interest to you:

Articles:

“HBV cccDNA: The Molecular Reservoir of Hepatitis B Persistence and Challenges to Achieve Viral Eradication”
by André Boonstra and Gulce Sari
Biomolecules 2025, 15(1), 62; https://doi.org/10.3390/biom15010062
Available online: https://www.mdpi.com/2218-273X/15/1/62

“G-Protein-Coupled Receptor (GPCR) Signaling and Pharmacology in Metabolism: Physiology, Mechanisms, and Therapeutic Potential”
by Yun Yeong Cho, Soyeon Kim, Pankyung Kim, Min Jeong Jo, Song-E Park, Yiju Choi, Su Myung Jung and Hye Jin Kang
Biomolecules 2025, 15(2), 291; https://doi.org/10.3390/biom15020291
Available online: https://www.mdpi.com/2218-273X/15/2/291

“Not Just an Alternative Energy Source: Diverse Biological Functions of Ketone Bodies and Relevance of HMGCS2 to Health and Disease”
by Varshini V. Suresh, Sathish Sivaprakasam, Yangzom D. Bhutia, Puttur D. Prasad, Muthusamy Thangaraju and Vadivel Ganapathy
Biomolecules 2025, 15(4), 580; https://doi.org/10.3390/biom15040580
Available online: https://www.mdpi.com/2218-273X/15/4/580

“Therapeutic Plasma Exchange: Current and Emerging Applications to Mitigate Cellular Signaling in Disease”
by R. M. Imtiaz Karim Rony, Alireza Shokrani, Naseeb Kaur Malhi, Deborah Hussey, Rachael Mooney, Zhen Bouman Chen, Tristan Scott, Haiyong Han, Jaeger Moore, Jiahui Liu et al.
Biomolecules 2025, 15(7), 1000; https://doi.org/10.3390/biom15071000
Available online: https://www.mdpi.com/2218-273X/15/7/1000

“State of the Art in the Standardization of Stromal Vascular Fraction Processing”
by Martina Cremona, Matteo Gallazzi, Giulio Rusconi, Luca Mariotta, Mauro Gola and Gianni Soldati
Biomolecules 2025, 15(2), 199; https://doi.org/10.3390/biom15020199
Available online: https://www.mdpi.com/2218-273X/15/2/199

“Carnitine O-Acetyltransferase as a Central Player in Lipid and Branched-Chain Amino Acid Metabolism, Epigenetics, Cell Plasticity, and Organelle Function”
by Mariateresa Volpicella, Maria Noemi Sgobba, Luna Laera, Anna Lucia Francavilla, Danila Imperia De Luca, Lorenzo Guerra, Ciro Leonardo Pierri and Anna De Grassi
Biomolecules 2025, 15(2), 216; https://doi.org/10.3390/biom15020216
Available online: https://www.mdpi.com/2218-273X/15/2/216

“Early-Stage Luminal B-like Breast Cancer Exhibits a More Immunosuppressive Tumor Microenvironment than Luminal A-like Breast Cancer”
by Tânia Moura, Olga Caramelo, Isabel Silva, Sandra Silva, Manuela Gonçalo, Maria Antónia Portilha, João N. Moreira, Ana M. Gil, Paula Laranjeira and Artur Paiva
Biomolecules 2025, 15(1), 78; https://doi.org/10.3390/biom15010078
Available online: https://www.mdpi.com/2218-273X/15/1/78

“Retinal Pigment Epithelium Transplantation in Retinal Disease: Clinical Trial Development, Challenges, and Future Directions”
by Qin Chen, Ting Zhang, Zhi Chen, Jingwen Zeng, Aine O’Connor, Meidong Zhu, Mark C. Gillies, Fang Lu and Ling Zhu
Biomolecules 2025, 15(8), 1167; https://doi.org/10.3390/biom15081167
Available online: https://www.mdpi.com/2218-273X/15/8/1167

“Mechanobiology in Action: Biomaterials, Devices, and the Cellular Machinery of Force Sensing”
by Miriam Lucariello, Maria Luisa Valicenti, Samuele Giannoni, Leonardo Donati, Ilaria Armentano, Francesco Morena and Sabata Martino
Biomolecules 2025, 15(6), 848; https://doi.org/10.3390/biom15060848
Available online: https://www.mdpi.com/2218-273X/15/6/848

“The Role of Astrocytes in the Molecular Pathophysiology of Schizophrenia: Between Neurodevelopment and Neurodegeneration”
by Licia Vellucci, Benedetta Mazza, Annarita Barone, Anita Nasti, Giuseppe De Simone, Felice Iasevoli and Andrea de Bartolomeis
Biomolecules 2025, 15(5), 615; https://doi.org/10.3390/biom15050615
Available online: https://www.mdpi.com/2218-273X/15/5/615

Special Issues:

“Biomolecules and Their Impact on Biology and Translational Applications: Celebrating the Pioneering Work of Prof. Ho Jeong Kwon”
Guest Editors: Dr. Eun-Woo Lee and Dr. Hye Jin Kang
Published papers: 11
Viewed by 30345+

“The Central Role of Mitochondrial Protein VDAC1 in Human Diseases – Honorary Special Issue Commemorating the Work of Prof. Varda Shoshan-Barmatz”
Guest Editor: Dr. Jay H. Chung
Published papers: 7
Viewed by 25620+

“Effects of Weightlessness on Molecular Changes in Cellular Organisms, Animals and Plants”
Guest Editor: Prof. Dr. Daniela Grimm
Published papers: 11
Viewed by 33645+

“Recent Developments in Mesenchymal Stem Cells”
Guest Editors: Dr. Antonietta Rosa Silini and Dr. Enrico Ragni
Published papers: 8
Viewed by 29955+

“Feature Papers in Cellular Biochemistry”
Guest Editor: Prof. Dr. Anna Rita Franco Migliaccio
Published papers: 9
Viewed by 24780+

“Advances in Cellular and Molecular Mechanisms in Immuno-Oncology and Onco-Hematology”
Guest Editor: Dr. Paolo Fagone
Published papers: 9
Viewed by 23480+

“Microbial Biocontrol and Plant-Microbe Interactions”
Guest Editor: Dr. Shahzad Munir
Published papers: 7
Viewed by 9060+

“Advances in Metal Binding Proteins”
Guest Editor: Dr. Eugene Permyakov
Published papers: 11
Viewed by 45435+

1 December is World AIDS Day, the day is an opportunity for public and private partners to spread awareness about the status of the pandemic and encourage progress in HIV/AIDS prevention, treatment, and care around the world. It has become one of the most widely recognized international health days.

In recognition of this day, we recommend the following related articles, Special Issues, and journals spanning multidisciplinary fields, including clinical medicine and biology. We believe that sharing such research can raise the public’s awareness and understanding of AIDS. The aim is to strengthen scientific cooperation in response to increased awareness about HIV/AIDS and to demonstrate international solidarity in the face of the pandemic.

“Progress and Challenges in HIV-1 Vaccine Research: A Comprehensive Overview”
by Alex C. Boomgarden and Chitra Upadhyay
Vaccines 2025, 13(2), 148; https://doi.org/10.3390/vaccines13020148

“Drug-Drug Interactions Between HIV Antivirals and Concomitant Drugs in HIV Patients: What We Know and What We Need to Know”
by Emanuela De Bellis, Danilo Donnarumma, Adele Zarrella, Salvatore Maria Mazzeo, Annarita Pagano, Valentina Manzo, Ines Mazza, Francesco Sabbatino, Graziamaria Corbi, Pasquale Pagliano et al.
Pharmaceutics 2025, 17(1), 31; https://doi.org/10.3390/pharmaceutics17010031

“High Prevalence of High-Risk HPV Among People with and Without HIV: Insights into Risk Factors for Tailored Screening Approaches”
by Elena Bruzzesi, Federica Gandini, Sara Diotallevi, Riccardo Lolatto, Massimo Cernuschi, Caterina Candela, Angelo Roberto Raccagni, Flavia Passini, Andrea Marco Tamburini, Roberto Burioni et al.
Microorganisms 2024, 12(12), 2571; https://doi.org/10.3390/microorganisms12122571

“Association Between Left Ventricular Diastolic Dysfunction, Systemic Inflammation, and Gastrointestinal Symptoms in HIV-Positive Patients on Antiretroviral Therapy”
by Madalina-Ianca Suba, Bogdan Hogea, Ahmed Abu-Awwad, Voichita Elena Lazureanu, Ovidiu Rosca, Daniela Gurgus, Sorina Maria Denisa Laitin and Alina Abu-Awwad
Diseases 2024, 12(12), 313; https://doi.org/10.3390/diseases12120313

“NSC95397 Is a Novel HIV-1 Latency-Reversing Agent”
by Randilea Nichols Doyle, Vivian Yang, Yetunde I. Kayode, Robert Damoiseaux, Harry E. Taylor and Oliver I. Fregoso
Viruses 2024, 16(11), 1783; https://doi.org/10.3390/v16111783

“HIV Self-Testing: A Discussion on the Benefits, Limitations, and Implications for Public Health with a Focus on Poland”
by Aleksandra Kozieł, Igor Domański, Aleksandra Szymczak, Tomasz Dudzik, Brygida Knysz and Bartosz Szetela
Diagnostics 2024, 14(22), 2475; https://doi.org/10.3390/diagnostics14222475

“Tumor Initiation and Progression in People Living on Antiretroviral Therapies”
by Seun E. Olufemi, Daniel A. Adediran, Temitope Sobodu, Isaac O. Adejumo, Olumide F. Ajani and Elijah K. Oladipo
Biologics 2024, 4(4), 390-406; https://doi.org/10.3390/biologics4040024

“J3ExoA: A Novel Anti-HIV Immunotoxin Fusion of Anti-Gp120 J3VHH and PE38 Fragment of Pseudomonas Exotoxin A”
by Seth H. Pincus, Kun Luo, Tami Peters, James T. Gordy, Frances M. Cole, Grant Klug, Kelli Ober, Tamera K. Marcotte and Richard B. Markham
Pharmaceuticals 2025, 18(9), 1305; https://doi.org/10.3390/ph18091305

“A Memo on Factors Associated with Perception of Stigma Attached to PrEP: Evidence from the Keeping It LITE Study”
by Shahin Davoudpour, Gregory L. Phillips II, Pedro A. Serrano, Audrey L. French and Sybil G. Hosek
Sexes 2024, 5(3), 300-316; https://doi.org/10.3390/sexes5030023

“Effects of E-Cigarettes on the Lung and Systemic Metabolome in People with HIV”
by Aline Zaparte, Courtney J. Christopher, Connie Arnold, Lauren Richey, Adairre Castille, Kyle Mistretta, Christopher M. Taylor, Huiyi Lin, Steve Nelson, John P. Kirwan, John W. Apolzan, Shawn R. Campagna and David A. Welsh
Metabolites 2024, 14(8), 434; https://doi.org/10.3390/metabo14080434

“Bone Tissue Changes in Individuals Living with HIV/AIDS: The Importance of a Hierarchical Approach in Investigating Bone Fragility”
by Jelena Jadzic, Gordana Dragovic, Relja Lukic, Bozana Obradovic and Marija Djuric
J. Pers. Med. 2024, 14(8), 791; https://doi.org/10.3390/jpm14080791

“Advanced Therapies for Human Immunodeficiency Virus”
by Daniel Josef Lindegger
Med. Sci. 2024, 12(3), 33; https://doi.org/10.3390/medsci12030033

“Antiretroviral Therapy Switch in HIV-Infected Adults from a Regional HIV/AIDS Center in NE Romania”
by Isabela Ioana Loghin, Șerban Alin Rusu, Andrei Vâţă, Mihaela Cobaschi, Ion Cecan, Carmen Manciuc and Carmen Mihaela Dorobăţ
Medicina 2024, 60(6), 854; https://doi.org/10.3390/medicina60060854

“Alterations in the Gut Microbiome Composition of People Living with HIV in the Asia–Pacific Region: A Systematic Review”
by Paul Benedic U. Salvador, Patrick Josemaria d. R. Altavas, Mark Angelo S. del Rosario, Eric David B. Ornos and Leslie Michelle M. Dalmacio
Clin. Pract. 2024, 14(3), 846-861; https://doi.org/10.3390/clinpract14030066

“Systematic Review: HIV, Aging, and Housing—A North American Perspective, 2012–2023”
by Arthur S. Chaminuka, Gayle Prybutok, Victor R. Prybutok and William D. Senn
Healthcare 2024, 12(10), 992; https://doi.org/10.3390/healthcare12100992

“The Role of MicroRNAs in HIV Infection”
by Nicolas Morando, Mara Cecilia Rosenzvit, Maria A. Pando and Jens Allmer
Genes 2024, 15(5), 574; https://doi.org/10.3390/genes15050574

“HIV-TB Co-Infection and Pediatric Pathogen Dynamics” Guest Editor: Dr. Boris Kevin Tchounga Submission deadline: 15 March 2026	“HIV Expression in Diverse Cell Types: Mechanisms, Regulation, and Pathogenesis” Guest Editor: Dr. Rosemary Kiernan Submission deadline: 20 March 2026
“Research on HIV/AIDS Vaccine” Guest Editors: Dr. Portia Chipo Mutevedzi and Dr. Nagesh Kolishetti Submission deadline: 31 May 2026	“Gene and Cell Therapy: New Findings from Medical Research and Treatment” Guest Editors: Dr. Lorella Tripodi and Dr. Antonio Di Stasi Submission deadline: 30 June 2026
“Emerging Knowledge on Human Immunodeficiency Virus” Guest Editors: Dr. Giota Lourida and Prof. Dr. Dimitrios Paraskevis Submission deadline: 22 July 2026	“Nutrition Intervention in HIV Patients” Guest Editors: Dr. Meena Mahadevan Submission deadline: 10 August 2026

In support of World Antimicrobial Resistance (AMR) Awareness Week 2025, MDPI is delighted to invite you to our special webinar, “MDPI World AMR Awareness Week Webinar 2025”. This year’s theme, “Act Now: Protect Our Present, Secure Our Future”, serves as a powerful call to immediate action against one of the most pressing global health threats—antimicrobial resistance.

Through this webinar, we aim to highlight the latest research, innovations, and cross-sector collaborations addressing AMR. We hope these discussions will inspire collective action to promote the prudent use of antimicrobials, strengthen prevention and surveillance systems, and accelerate global efforts to safeguard human, animal, and environmental health.

Thank you for joining us as we raise awareness, exchange insights, and reaffirm our shared commitment to a healthier, more resilient future.

keywords: antimicrobial resistance; antifungal resistance; food chain contamination; biofilm infections; nanomedicine; microbial genetics; mycology; public health

Date: 21 November 2025
Time: 9:00 a.m. CET | 4:00 p.m. CST (Asia)
Webinar ID: 883 6849 1341
Webinar Secretariat: journal.webinar@mdpi.com

Register now for free!

Program:

After registering, you will receive a confirmation email on how to join the webinar. Registrations with academic institutional email addresses will be prioritized.

Unable to attend? Register anyway, and we will let you know when the recording is available for viewing.

Webinar Speakers:

• Dr. José Cobo-Díaz, Department of Food Hygiene and Technology, University of Leon, Spain;
• Dr. Ana Alastruey-Izquierdo, National Microbiology Center, Carlos III Health Institute, Spain;
• Dr.  Anam Ahsan, Clinical & Health Sciences / Centre for Pharmaceutical Innovation, University of South Australia, Australia;
• Prof. Dr. Michaela Lackner, Medical University of Innsbruck (MUI), Institute of Hygiene and Medical Microbiology (HMM), Austria;
• Dr.  Elena Perrin, Department of Biology, University of Florence, Italy.

World AMR Awareness Day 2025 draws attention to the urgent global challenge of antimicrobial resistance (AMR)—one of the greatest threats to public health, food security, and sustainable development. This year’s theme, “Act Now: Protect Our Present, Secure Our Future”, calls on the international community to take immediate, coordinated, and sustained action to preserve the effectiveness of life-saving antimicrobials. AMR affects every region of the world and every aspect of modern medicine, from surgery and cancer therapy to animal health and agriculture. Without effective antibiotics, common infections and minor injuries could once again become deadly.

To address this growing crisis, selected MDPI journals provide leading platforms for advancing research on antimicrobial resistance, surveillance, stewardship, and innovative therapeutic strategies. These include studies on new antibiotics, resistance mechanisms, diagnostic tools, infection control, and global policy frameworks. Through curated articles, Special Issues, and reprints, these journals foster cross-disciplinary collaboration among researchers, clinicians, and policymakers to combat AMR through innovation, education, and evidence-based practice.

World AMR Awareness Day serves as a powerful reminder that tackling antimicrobial resistance requires shared responsibility, sustained investment in research and innovation, and collective global action to secure a healthier, more resilient future for all.

“Antibacterial, Antifungal, Antiviral Activity, and Mechanisms of Action of Plant Polyphenols”
by Slavena Davidova, Angel S. Galabov and Galina Satchanska
Microorganisms 2024, 12(12), 2502; https://doi.org/10.3390/microorganisms12122502 

”An Overview of the Recent Advances in Antimicrobial Resistance”
by Manuela Oliveira, Wilson Antunes, Salete Mota, Áurea Madureira-Carvalho, Ricardo Jorge Dinis-Oliveira and Diana Dias da Silva
Microorganisms 2024, 12(9), 1920; https://doi.org/10.3390/microorganisms12091920

“A Mini-Review of In Vitro Data for Candida Species, Including C. auris, Isolated during Clinical Trials of Three New Antifungals: Fosmanogepix, Ibrexafungerp, and Rezafunesgin”
by Ana Espinel-Ingroff and Nathan P. Wiederhold
J. Fungi 2024, 10(5), 362; https://doi.org/10.3390/jof10050362

“ESKAPE: Navigating the Global Battlefield for Antimicrobial Resistance and Defense in Hospitals”
by Kamna Ravi and Baljit Singh
Bacteria 2024, 3(2), 76-98; https://doi.org/10.3390/bacteria3020006

Special Issues:

“A Six-Step Protocol for Monitoring Antimicrobial Resistance Trends Using WHONET and R: Real-World Application and R Code Integration”
by Fabio Ingravalle, Antonio Vinci, Marco Ciotti, Carla Fontana, Francesca Pica, Emanuele Sebastiani, Clara Donnoli, Martino Guido Rizzo, Dario Tedesco, Silvia D’Arezzo et al.
Methods Protoc. 2025, 8(5), 115; https://doi.org/10.3390/mps8050115 

“Improved Prognostic Accuracy of NEWS2 Score with Triage Data in Adults with Bacterial Sepsis: A Retrospective Cohort Study”
by Pietro Pozzessere, Roberto Lovero, Corrado Crocetta, Najada Firza, Vincenzo Brescia, Angela Pia Cazzolla, Mario Dioguardi, Francesco Testa, Marica Colella and Luigi Santacroce
Int. J. Transl. Med. 2025, 5(4), 44; https://doi.org/10.3390/ijtm5040044

“Prevalence and Antimicrobial Resistance of Typhoid Fever in Ghana: A Systematic Review and Meta-Analysis”
by Frederick Kungu, Aaron Awere-Duodu and Eric S. Donkor
Diseases 2025, 13(4), 113; https://doi.org/10.3390/diseases13040113

“Antimicrobial Resistance Patterns and Biofilm Analysis via Sonication in Intensive Care Unit Patients at a County Emergency Hospital in Romania”
by Ioana Roxana Codru, Bogdan Ioan Vintilă, Alina Simona Bereanu, Mihai Sava, Livia Mirela Popa and Victoria Birlutiu
Pharmaceuticals 2025, 18(2), 161; https://doi.org/10.3390/ph18020161 

Special Issues:

“Antimicrobial and Anti-Inflammatory Potentials of Silver Tungstate Nanoparticles, Cytotoxicity and Interference on the Activity of Antimicrobial Drugs”
by Washington de Souza Leal, Juliane Zacour Marinho, Isabela Penna Ceravolo, Lucas Leão Nascimento, Antonio Otávio de Toledo Patrocínio and Marcus Vinícius Dias-Souza
Drugs Drug Candidates 2025, 4(3), 30; https://doi.org/10.3390/ddc4030030

“Release Profile and Antibacterial Activity of Thymus sibthorpii Essential Oil-Incorporated, Optimally Stabilized Type I Collagen Hydrogels”
by Caglar Ersanli, Ioannis Skoufos, Konstantina Fotou, Athina Tzora, Yves Bayon, Despoina Mari, Eleftheria Sarafi, Konstantina Nikolaou and Dimitrios I. Zeugolis
Bioengineering 2025, 12(1), 89; https://doi.org/10.3390/bioengineering12010089

“Antimicrobial Peptides from Frogs of the Glandirana Genus”
by Frederick Harris, David A. Phoenix and Sarah R. Dennison
Biologics 2024, 4(4), 444-507; https://doi.org/10.3390/biologics4040027

“Phytochemical Composition and Antimicrobial and Antibiofilm Effect of Myrciaria cauliflora Hydroethanolic Extract against Staphylococcus aureus and Acinetobacter baumannii”
by Luciane Dias de Oliveira, Ana Luisa Monteiro Ribeiro, Sthéfani de Oliveira Dias, Geovani Moreira da Cruz, Raquel Teles de Menezes, Lara Steffany de Carvalho, Mariana Gadelho Gimenez Diamantino, Thaís Cristine Pereira, Maria Cristina Marcucci and Amjad Abu Hasna
Methods Protoc. 2024, 7(4), 60; https://doi.org/10.3390/mps7040060

“LL-37: Structures, Antimicrobial Activity, and Influence on Amyloid-Related Diseases”
by Surajit Bhattacharjya, Zhizhuo Zhang and Ayyalusamy Ramamoorthy
Biomolecules 2024, 14(3), 320; https://doi.org/10.3390/biom14030320

Special Issues:

“Antimicrobial Resistance Gene Patterns in Traditional Montenegrin Njeguški Cheese Revealed by qPCR”
by Vesna Milanović, Giorgia Rampanti, Andrea Cantarini, Federica Cardinali, Giuseppe Paderni, Aleksandra Martinovic, Andrea Brenciani, Lucia Aquilanti, Andrea Osimani and Cristiana Garofalo
Genes 2025, 16(9), 1089; https://doi.org/10.3390/genes16091089

“Immunotherapy Potential of Animal-Sourced Probiotic Bacteria”
by Isaac Oluseun Adejumo
Biologics 2025, 5(3), 17; https://doi.org/10.3390/biologics5030017

“Screening and Genomic Profiling of Antimicrobial Bacteria Sourced from Poultry Slaughterhouse Effluents: Bacteriocin Production and Safety Evaluation”
by Nuria Peña, Irene Lafuente, Ester Sevillano, Javier Feito, Diogo Contente, Estefanía Muñoz-Atienza, Luis M. Cintas, Pablo E. Hernández and Juan Borrero
Genes 2024, 15(12), 1564; https://doi.org/10.3390/genes15121564 

“The Impact of Antibiotics and Steroids on the Nasal Microbiome in Patients with Chronic Rhinosinusitis: A Systematic Review According to PICO Criteria”
by Antonella Loperfido, Carlo Cavaliere, Elona Begvarfaj, Andrea Ciofalo, Giovanni D’Erme, Marco De Vincentiis, Antonio Greco, Stefano Millarelli, Gianluca Bellocchi and Simonetta Masieri
J. Pers. Med. 2023, 13(11), 1583; https://doi.org/10.3390/jpm13111583

Special Issues:

Med. Sci. Forum, 2025, ECA 2025 The 4th International Electronic Conference on Antibiotics Organiser: MDPI and Antibiotics Volume Editors: Manuel Simões and Marc Maresca Highlights Fourier Transform Infrared Spectroscopy-Based Detection of Amoxicillin and Ampicillin for Advancing Antibiotic Monitoring with Optical Techniques by Vinicius Pereira Anjos et al. Third-Generation Cephalosporin-Resistant Escherichia coli Isolates Belonging to High-Risk Clones Obtained from Fresh Pork Meat in La Plata City, Argentina by Hernán D. Nievas et al. Click here to read the full list of papers.