Search Results (27)

The following work is based on the historical–anthropological analysis of 93 skeletal remains belonging to post-war casualties who died in 1946 and remained missing for years. In 2019, 93 metal boxes containing skeletal remains of Slavic origin, belonging to civilians and soldiers who perished in the immediate postwar period following World War II, were found inside the ossuary of the Monumental Cemetery in Bari (Italy). At the beginning of the search, these people were thought to have died in prison camps in Apulia, such as Torre Tresca and Grumo Appula, in the province of Bari. Later, thanks to the discovery of war badges and years of extensive historical research, it was discovered that these remains had been missing for 75 years and belonged to soldiers of the Royal Yugoslav Army and civilians, probably their relatives, who died in 1946 in the refugee camp of Eboli, in the province of Salerno, Campania (Italy). To unveil this truth that remained hidden for over 75 years, a multidisciplinary study divided into two phases was applied. The first phase, grounded in historical research study, aimed to determine the historical and temporal context in which they lived and confirm the life they actually lived in the Eboli refugee camp. The second phase, grounded in anthropological research, aimed to reconstruct the biological profile of each individual, identify the presence of antemortem, perimortem, and postmortem lesions, assess potential pathological conditions, and determine, where possible, the cause of death. Finally, a correlation of the collected data was conducted to ascertain and corroborate, with reasonable certainty, the living conditions to which they were subjected in the refugee camp where they resided. Italy after 1943 became the scene of intense fighting and a dramatic situation for prisoners of war, including many Yugoslav soldiers. This work brought to light a history that had been lost for as many as 75 years, highlighted the importance, specifically, of the role of the Eboli refugee camp, a context little known and forgotten by many, and above all made it possible to remember and restore dignity to the victims of the Great War. Full article

The growing threat of antimicrobial resistance (AMR) is a critical issue for both civilians and the military. With each successive conflict, pathogens become more resistant, making the management of infections in casualties increasingly challenging. To better understand the scope and characteristics of conflict-related AMR, a comprehensive literature search was conducted in the PubMed database in April 2025, using defined search terms related to war casualties and antimicrobial resistance. We screened and included 117 relevant publications, comprising original research articles, reviews, case series, case reports, editorials, and commentaries, published in English or French, with no date restriction. This narrative review synthesizes current evidence on multidrug-resistant bacteria most commonly isolated from war casualties, their associated resistance mechanisms, and the microbiological diagnostic tools available at various levels of the military continuum of care (Roles 1–4). It also presents strategies for preventing cross-contamination and infection in resource-limited combat settings and provides practical, field-adapted recommendations for clinicians, from first responders to specialized care providers, aiming to improve infection management in armed conflict zones and mitigate the spread of AMR. Full article

Background: Warfare represents a significant source of stress in contemporary times, with enduring implications beyond the immediate casualties, fostering a pervasive atmosphere of danger and anxiety within affected populations. The Israel–Hamas war, marked by ongoing armed incursions and missile attacks, stands as a recent example of such turmoil, inflicting widespread trauma and disruption. Methods: This study, conducted among students at the Ashkelon Academic College in southern Israel, aimed to investigate the stress levels and associated factors amidst the ongoing conflict. Utilizing a cross-sectional survey design, data were collected from 625 participants between January and February 2024, approximately four months after the commencement of the initial attack. The survey encompassed demographic information, perceived stress levels, sleep quality, and social media usage. Results: The findings revealed moderate to high stress levels among participants, with significant differences observed based on gender, parental status, and residency in conflict zones. Moreover, poorer sleep quality was reported among students residing in conflict-affected areas. Regression analysis identified several predictors of elevated stress, including gender, parental status, sleep quality, residency in conflict zones, and social media usage. Conclusions: These findings underscore the profound impact of ongoing conflict on college students’ mental well-being, highlighting the need for tailored interventions and support services within higher education institutions. The limitations include the study’s focus on a specific college population and the timing of the data collection relative to the onset of the war. Nonetheless, this research contributes valuable insights concerning the stress dynamics within the unique context faced by Israeli students amidst ongoing warfare. Full article

The paper examines a paradigmatic example of post-conflict economic development of Vukovar, Croatia. It represents a pertinent case study for localities encountering analogous challenges, most notably urban areas in Ukraine in the near future. The war that broke out in 1991 brought significant human casualties, population displacement, and extensive destruction of residential, social, and economic infrastructure. The completion of the peaceful reintegration of Vukovar into Croatia’s legal system in 1998 marked the beginning of the socio-economic revitalization process. The research scrutinizes the primary impediments and prospects for Vukovar’s economic growth, probing why substantial investments in reconstructing housing, transport, communal infrastructure, and fiscal incentives for businesses have not paralleled its economic performance. It concentrates on the local business climate and influential factors as potential explanations for this discrepancy. The topic was designed as a case study and was covered by document analysis, survey method, and semi-structured interviews. Utilizing a mixed-methods approach, the study collates perspectives from entrepreneurs and business support institutions. The results confirmed that reconstruction of housing and social infrastructure is necessary, but more conditions are needed for successful post-conflict economic development, and that the business climate in lagging local units highly depends on state- and locally designed business-support measures. Full article

New and efficient sensors of nerve agents are urgently demanded to prevent them from causing mass casualties in war or terrorist attacks. So, in this work, a novel hierarchical nanoheterostructure was synthesized via the direct growth of α-Fe₂O₃ nanorods onto multiwall carbon nanotube (MWCNT) backbones. Then, the composites were functionalized with hexafluoroisopropanol (HFIP) and successfully applied to detect dimethyl methylphosphonate (DMMP)-sarin simulant gas. The observations show that the HFIP-α-Fe₂O₃@MWCNT hybrids exhibit outstanding DMMP-sensing performance, including low operating temperature (220 °C), high response (6.0 to 0.1 ppm DMMP), short response/recovery time (8.7 s/11.9 s), as well as low detection limit (63.92 ppb). The analysis of the sensing mechanism demonstrates that the perfect sensing performance is mainly due to the synergistic effect of the chemical interaction of DMMP with the heterostructure and the physical adsorption of DMMP by hydrogen bonds with HFIP that are grafted on the α-Fe₂O₃@MWCNTs composite. The huge specific surface area of HFIP-α-Fe₂O₃@MWCNTs composite is also one of the reasons for this enhanced performance. This work not only offers a promising and effective method for synthesizing sensitive materials for high-performance gas sensors but also provides insight into the sensing mechanism of DMMP. Full article

Throughout history, seafarers have been exposed to potential thermal injuries during naval warfare; however, injury prevention, including advances in personal protective equipment, has saved lives. Thankfully, burn injuries have decreased over time, which has resulted in a significant clinical skills gap. Ships with only Role 1 (no surgical capability) assets have worse outcomes after burn injury compared to those with Role 2 (surgical capability) assets. To prepare for future burn care challenges during a war at sea, Military Medicine must re-learn the lessons of World War I and World War II. Burn injuries do not occur in isolation during war and are associated with concomitant traumatic injuries. To care for burn casualties at sea, there is an urgent need to increase the availability of whole blood and dried plasma, resuscitation fluids that were ubiquitous throughout the naval force during World War II for both hemorrhagic and burn shock resuscitation. Furthermore, those providing trauma care at sea require formal burn care training and skills sustainment experiences in the clinical management of Burn, Trauma, and Critical Care patients. While burn education, training, and experience must be improved, modern high-energy weapons systems and anti-ship ballistic missiles necessitate concurrent investments in prevention, countermeasures, and personal protective equipment to decrease the likelihood of burn injury and damage resulting from these attacks. Full article

Dried urine spot (DUS) is a micro-sample collection technique, known for its advantages in handling, storage and shipping. It also uses only a small volume of urine, an essential consideration in working with small animals, or in acute medical situations. Alkyl-phosphonic acids are the direct and indicative metabolites of organophosphorus chemical warfare agents (OP-CWAs) and are present in blood and urine shortly after exposure. They are therefore crucially important for monitoring casualties in war and terror scenarios. We report here a new approach for the determination of the metabolites of five CWAs in urine using DUS. The method is based on a simple and rapid sample preparation, using only 50 µL of urine, spotted and dried on DBS paper, extracted using 300 µL methanol/water and analyzed via targeted LC-MS/MS. The detection limits for the five CWAs, sarin (GB), soman (GD), cyclosarin (GF), VX and RVX in human urine were from 0.5 to 5 ng/mL. Recoveries of (40–80%) were obtained in the range of 10–300 ng/mL, with a linear response (R² > 0.964, R > 0.982). The method is highly stable, even with DUS samples stored up to 5 months at room temperature before analysis. It was implemented in a sarin in vivo exposure experiment on mice, applied for the time course determination of isopropyl methylphosphonic acid (IMPA, sarin hydrolysis product) in mice urine. IMPA was detectable even with samples drawn 60 h after the mice’s (IN) exposure to 1 LD₅₀ sarin. This method was also evaluated in a non-targeted screening for multiple potential CWA analogs (LC-Orbitrap HRMS analysis followed by automatic peak detection and library searches). The method developed here is applicable for rapid CWA casualty monitoring. Full article

The ravaging COVID-19 pandemic has almost pushed into oblivion the fact that the United States is still struggling with an immense addiction crisis. Drug overdose deaths rose from 16,849 in 1999 to nearly 110,000—of which an estimated 75,000 involved opioids—in 2022. On a yearly basis, the opioid casualty rate is higher than the combined number of victims of firearm violence and car accidents. The COVID-19 epidemic might have helped to worsen the addiction crisis by stimulating drug use among adolescents and diverting national attention to yet another public health crisis. In the past decade, the sharpest increase in deaths occurred among those related to fentanyl and fentanyl analogs (illicitly manufactured, synthetic opioids of greater potency). In the first opioid crisis wave (1998–2010), opioid-related deaths were mainly associated with prescription opioids such as Oxycontin (oxycodone hydrochloride). The mass prescription of these narcotic drugs did anything but control the pervasive phenomenon of ‘addiction on prescription’ that played such an important role in the emergence and robustness of the US opioid crisis. Using a long-term drug lifecycle analytic approach, in this article I will show how opioid-producing pharmaceutical companies created a medical market for opioid painkillers. They thus fueled a consumer demand for potent opioid drugs that was eagerly capitalized on by criminal entrepreneurs and their international logistic networks. I will also point out the failure of US authorities to effectively respond to this crisis due to the gap between narcotic product regulation, regulation of marketing practices and the rise of a corporate-dominated health care system. Ironically, this turned the most powerful geopolitical force in the war against drugs into its greatest victim. Due to formulary availability and regulatory barriers to accessibility, European countries have been relatively protected against following suit the US opioid crisis. Full article

The consequences of dam damage caused by explosions, wars, and terrorist attacks are extremely serious, and they can cause casualties among downstream residents. Studying the damage behaviors of dams is a prerequisite for improving their anti-knock performance. Researchers view the dam as homogeneous for research; but in reality, the concrete strength of the dam decreases from bottom to top. The partitioning of dam concrete strength can meet the different functional and economic requirements of a concrete gravity dam (referred to as concrete strength partition gravity dam (CSPGD)). Therefore, CSPGD shows a more complex dynamic performance and failure characteristics under the impact load of an underwater explosion. First, by investigating the current status of anti-knock research on CSPGDs, a fully coupled finite element numerical model for an underwater explosion of CSPGD was established. Considering the initial stress such as the self-weight of the dam, the upstream reservoir hydrostatic pressure, and the uplift pressure of the dam foundation during the service period, the anti-knock performance of CSPGD was studied. The results showed that the interface of CSPGD had a strain rate effect under the action of blast load, and it was easy to produce tensile failure at a low strain rate. In addition, the dynamic response and damage characteristics under different explosion scenarios such as explosive charge weight (w), detonation depth (D), and standoff distance (R) were further studied. The dam crest was always a weak anti-knock part, and the foundation anti-sliding stability was also very important to dam safety. Therefore, it was proposed and suggested to use the crack length of the dam crest and dam foundation to evaluate the overall anti-knock capacity of CSPGD. The study also found that the detonation depth affected the response time of dam damage and had a significant impact on the anti-knock performance of CSPGD. Full article

Sulfur mustard gas (SM) is a vesicating and alkylating agent used as a chemical weapon in many mass-casualty incidents since World War I. Ocular injuries were reported in >90% of exposed victims. The mechanisms underlying SM-induced blindness remain elusive. This study tested the hypothesis that SM-induced corneal fibrosis occurs due to the generation of myofibroblasts from resident fibroblasts via the SMAD2/3 signaling pathway in rabbit eyes in vivo and primary human corneal fibroblasts (hCSFs) isolated from donor corneas in vitro. Fifty-four New Zealand White Rabbits were divided into three groups (Naïve, Vehicle, SM-Vapor treated). The SM-Vapor group was exposed to SM at 200 mg-min/m3 for 8 min at the MRI Global facility. Rabbit corneas were collected on day 3, day 7, and day 14 for immunohistochemistry, RNA, and protein lysates. SM caused a significant increase in SMAD2/3, pSMAD, and ɑSMA expression on day 3, day 7, and day 14 in rabbit corneas. For mechanistic studies, hCSFs were treated with nitrogen mustard (NM) or NM + SIS3 (SMAD3-specific inhibitor) and collected at 30 m, 8 h, 24 h, 48 h, and 72 h. NM significantly increased TGFβ, pSMAD3, and SMAD2/3 levels. On the contrary, inhibition of SMAD2/3 signaling by SIS3 treatment significantly reduced SMAD2/3, pSMAD3, and ɑSMA expression in hCSFs. We conclude that SMAD2/3 signaling appears to play a vital role in myofibroblast formation in the cornea following mustard gas exposure. Full article

Novichoks-organophosphorus compounds belong to the nerve agents group, constituting the fourth generation of chemical warfare agents. The tremendous toxicity of Novichoks is assumed to be several times greater than that of VX, whereas no published experimental research supports this. They were surreptitiously created during the Cold War by the Soviet Union. Novichok’s toxic action mechanism consists of the inhibition of acetylcholinesterase activity. The review includes data on treating poisoning caused by OPs which could be used as guidelines for the therapy in case of Novichok exposure and HAZMAT/CBRNE approaches. Novichoks pose a severe threat due to their toxicity; however, there is insufficient information about the identity of A-series nerve agents. Filling in the missing data gaps will accelerate progress in improving protection against Novichoks and developing optimal therapy for treating poisoning casualties. Furthermore, introducing solutions to protect medical personnel in contact with a hazardous substance increases the chances of saving casualties of HAZMAT/CBRNE incidents. Full article

The Prophet of Islam, Muhammad, is depicted through extremely polar interpretations. Some perceive his life as a source for peace-making societies, whereas others portray him as a “warmonger” or “Prophet of the sword”, and use his examples to justify violence and terrorist attacks. The major incidents referred to in the latter context are the wars and conflicts that occurred after his migration to Medina. These conflicts are also prominent in sīrah narratives of his Medinan life from classical and modern periods. One can argue that there is a significant difference in the way Prophet Muhammad acted in Medina compared to the Meccan period. This is mostly attributed to the power balance, as the Muslims had little power in Mecca, which resulted in them enduring adversities, including verbal insults and physical torture while remaining peaceful and non-violent. In Medina, however, the Muslims obtained relatively more power and behaved differently. The main criticism of the Prophet at this juncture is that he took advantage of this power and became violent; this is the reason all the battles fall in his Medinan life. This article examines the root causes of his behaviour and shift in attitude. It clarifies the Prophet’s goal and agenda at this stage of his life. The article highlights his attitude towards peace and war by holistically analysing the battles and skirmishes that unfolded during the Medinan period. It examines the time spent on war and peace throughout his prophetic mission. In doing so, it enumerates statistical data, such as the number of battlefield casualties and those from expeditions. To attain accurate information in this regard, classical sīrah works and modern research on the battles are referred to as the main resources. Full article

Landmines and explosive remnants of war pose a global humanitarian problem and cause numerous casualties long after the conflict has ended. The current approaches for locating landmines, such as metal detection, which require one’s physical presence at the minefield, involve high risk to personnel; these methods are also costly, time-consuming, and have a high rate of false-positive results. There is no currently viable technology for the remote detection of buried explosive devices. A possible solution to this may be the use of genetically engineered microorganisms, molecularly “tailored” to emit an optical signal in the presence of trace explosives escaping for the landmine and accumulating in the soil above it. This optical signal, imaged from a remote location, can then be used to generate a physical map of the mine’s location. A few years ago, we have described the remote detection of buried landmines using alginate-encapsulated fluorescent microbial (Escherichia coli) bioreporters spread over the tested minefield. Since then, we have modified the system to one based on bioluminescent (rather than fluorescent) bacteria and have employed several synthetic biology approaches to significantly enhance their major performance parameters: higher signal intensity, faster response time, and lower detection threshold of the target explosives. These molecular approaches and their effect on sensor performance will be described. Full article

This paper explores the impact of the Great War (1914–1918) on Christianity in Scotland. This includes the attitudes of various denominations to the war, the rise and fall of religious attendance, and the impact of the war on Sabbatarianism, Sunday schools, church attendance, theology, and social and moral issues in Scottish society. Full article